(E)-hex-4-en-3-ol | 29478-27-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (E)-hex-4-en-3-ol
• 英文别名: Δ²-Hexenol-(4)；trans-4-hexen-3-ol；2-Hexen-4-ol
• CAS: 29478-27-1
• 化学式: C₆H₁₂O
• 分子量: 100.161
• InChiKey: KWUXUOPPQQMMIL-HWKANZROSA-N

物化性质

• 沸点：
  133-134 °C
• 密度：
  0.8367 g/cm3(Temp: 25 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  7
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (E)-hex-4-en-3-ol 在 镍 作用下， 生成 3-己酮
  参考文献：
  名称：

  Paul, Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1939, vol. 208, p. 1320

  摘要：

  DOI：
• 作为产物：
  描述：

  己烷-2,3,4-三醇 在 甲酸 作用下， 生成 (E)-hex-4-en-3-ol
  参考文献：
  名称：

  Delaby; Morel, Bulletin de la Societe Chimique de France, 1926, vol. <4>39, p. 419

  摘要：

  DOI：

文献信息

• Intramolecular activation of a N-methyl C–H bond by an electron rich iridium centre a novel chemoselective reduction catalyst
  作者：Erica Farnetti、Giorgio Nardin、Mauro Graziani

  DOI：10.1039/c39890001264

  日期：——

  The iridium complex H2[graphic omitted]H2Me][(P)–NMe2]}[(P)–NMe2=o-(diphenylphosphino)-N,N-dimethyl aniline] formed by intramolecular C-H oxidative addition, as shown by X-ray analysis, behaves as a chemoselective catalyst in hydrogen transfer reduction of α,β-unsaturated ketones to unsaturated alcohols.

  分子内CH氧化加成形成的铱配合物H 2 [省略图] H 2 Me] [（P）–NMe 2 ]} [（P）–NMe 2 =邻-（二苯基膦基）-N，N-二甲基苯胺]如通过X射线分析所示，在将α，β-不饱和酮氢转移还原为不饱和醇中，起化学选择性催化剂的作用。
• Reducing Characteristics of Borohydride Exchange Resin–CuSO₄in Methanol
  作者：Tae Bo Sim、Nung Min Yoon

  DOI：10.1246/bcsj.70.1101

  日期：1997.5

  characteristics of borohydride exchange resin (BER)–CuSO4 (cat.) were studied in methanol at room temperature. Carbon–carbon double bonds conjugated with benzene or carbonyl group were more rapidly reduced than was the case with isolated double bonds. Carbonyl groups were readily reduced, whereas esters and amides were inert, and nitriles were slowly reduced. High chemoselectivity was also observed in halide reductions:

  在室温下在甲醇中研究了硼氢化物交换树脂 (BER)–CuSO4（催化剂）的还原特性。与苯或羰基共轭的碳碳双键比分离双键的还原速度更快。羰基很容易被还原，而酯和酰胺是惰性的，而腈则被缓慢还原。在卤化物还原中也观察到了高化学选择性：对溴氯苯和对溴碘苯分别被定量还原为氯苯和溴苯。脂肪族环氧化物对该试剂呈惰性；然而，氧化苯乙烯衍生物很容易还原成相应的脱氧产物。脂肪族叠氮化物在 6 小时内缓慢还原，而苯基叠氮化物在 1 小时内转化为苯胺。硝基环己烷在室温下被还原，但硝基苯、亚硝基苯、偶氮苯和偶氮苯需要升高的温度 (65 °C) 才能快速还原 (1 小时)。同样，N,N-二甲基苯胺N...
• Gold(I)-Catalyzed Highly Regio- and Stereoselective Decarboxylative Amination of Allylic <i>N</i>-Tosylcarbamates via Base-Induced Aza-Claisen Rearrangement in Water
  作者：Dong Xing、Dan Yang

  DOI：10.1021/ol100056f

  日期：2010.3.5

  A gold(I)-catalyzed decarboxylative amination of allylic N-tosylcarbamates via base-induced aza-Claisen rearrangement has been developed. A variety of substituted N-tosyl allylic amines were obtained in good yield, excellent regioselectivity, and high to excellent stereoselectivity. This transformation could be performed either in H2O or in one pot directly from allylic alcohols and therefore represents

  已经开发了通过碱诱导的氮杂-克莱森重排的金（I）催化的烯丙基N-甲苯磺酰基氨基甲酸酯的脱羧胺化。以良好的产率，优异的区域选择性以及高至优异的立体选择性获得了各种取代的N-甲苯磺酰基烯丙基胺。该转化既可以在H 2 O中进行，也可以在一个罐中直接从烯丙基醇中进行，因此代表了合成N-甲苯磺酰基烯丙基胺的有效且环境友好的方案。
• [EN] AZABICYCLIC(THIO)AMIDES AS FUNGICIDAL COMPOUNDS<br/>[FR] (THIO)AMIDES AZABICYCLIQUES EN TANT QUE COMPOSÉS FONGICIDES
  申请人：BAYER AG

  公开号：WO2021233861A1

  公开（公告）日：2021-11-25

  The present invention relates to azabicyclic (thio)amide compounds and the uses thereof for controlling phytopathogenic microorganisms such as phytopathogenic fungi. It also relates to processes and intermediates for preparing these compounds

  本发明涉及吡啶环(硫)酰胺化合物及其用途，用于控制植物病原微生物，如植物病原真菌。它还涉及制备这些化合物的过程和中间体。
• Reduction of α,β-Unsaturated Ketones with Diphenylsilanes Bearing Several Substituents on Their Phenyl Moiety Catalyzed by Rhodium–Phosphine Complexes
  作者：Daisuke Imao、Miyuki Hayama、Kohta Ishikawa、Tetsuo Ohta、Yoshihiko Ito

  DOI：10.1246/cl.2007.366

  日期：2007.3.5

  1,4-Addition product was afforded exclusively by rhodium-phosphine complex-catalyzed hydrosilylation by using 2-cyclohexen-1-one and a dihydrosilane bearing an ether substituent in spite of the fact that dihydrosilanes were believed to give 1,2-addition product selectively.

  1,4-加成产物仅通过使用 2-环己烯-1-酮和带有醚取代基的二氢硅烷进行铑-膦配合物催化的氢化硅烷化作用而得到，尽管人们认为二氢硅烷会产生 1,2-加成产物有选择地。

表征谱图