(9Z)-10-ethoxydeca-5,9-dien-1-ol | 324538-05-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (9Z)-10-ethoxydeca-5,9-dien-1-ol
• 英文别名: (5Z,9Z)-10-ethoxydeca-5,9-dien-1-ol
• CAS: 324538-05-8
• 化学式: C₁₂H₂₂O₂
• 分子量: 198.305
• InChiKey: QHTFHUWWWCPIOC-PVMLHGRISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (9Z)-10-ethoxydeca-5,9-dien-1-ol 、 2-((S)-2-Benzyloxy-1-hydroxymethyl-ethyl)-[2,7]naphthyridin-2-ium; chloride 以 1,4-二氧六环 、 水 为溶剂， 反应 72.0h， 生成 (Z)-8-[(1R,8R,9S,12R,14R,15R)-15-ethoxy-12-(phenylmethoxymethyl)-10-oxa-4,13-diazatetracyclo[6.5.2.02,7.09,13]pentadeca-2(7),3,5-trien-14-yl]oct-5-en-1-ol 、 (Z)-8-[(1S,8S,9S,12R,14S,15S)-15-ethoxy-12-(phenylmethoxymethyl)-10-oxa-4,13-diazatetracyclo[6.5.2.02,7.09,13]pentadeca-2(7),3,5-trien-14-yl]oct-5-en-1-ol
  参考文献：
  名称：

  New developments in asymmetric Bradsher cycloadditions: use of chiral dienes

  摘要：

  Several serinol derivatives have been prepared and condensed following the Zincke reaction with 2,7-naphthyridine. The resulting naphthyridinium salts were engaged in Bradsher cycloadditions with enol ethers and afforded tetracyclic adducts, potential synthetic precursors of manzamine A alkaloid. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)01708-1
• 作为产物：
  描述：

  6-(叔-丁基二甲基硅烷基氧基)-1-己炔 在 Lindlar's catalyst 咪唑 、 甲基锂 、 氢气 、 碘 、 仲丁基锂 、 barium trifluoromethanesulfonate 、 三苯基膦 作用下， 以 四氢呋喃 、 喹啉 为溶剂， 生成 (9Z)-10-ethoxydeca-5,9-dien-1-ol
  参考文献：
  名称：

  New developments in asymmetric Bradsher cycloadditions: use of chiral dienes

  摘要：

  Several serinol derivatives have been prepared and condensed following the Zincke reaction with 2,7-naphthyridine. The resulting naphthyridinium salts were engaged in Bradsher cycloadditions with enol ethers and afforded tetracyclic adducts, potential synthetic precursors of manzamine A alkaloid. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)01708-1

文献信息

• New developments in asymmetric Bradsher cycloadditions: use of chiral dienes
  作者：Dominique Urban、Eric Duval、Yves Langlois

  DOI：10.1016/s0040-4039(00)01708-1

  日期：2000.11

  Several serinol derivatives have been prepared and condensed following the Zincke reaction with 2,7-naphthyridine. The resulting naphthyridinium salts were engaged in Bradsher cycloadditions with enol ethers and afforded tetracyclic adducts, potential synthetic precursors of manzamine A alkaloid. (C) 2000 Elsevier Science Ltd. All rights reserved.