2-Hydroxy-4-n-dodecoxybenzoesaeure | 86841-00-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Hydroxy-4-n-dodecoxybenzoesaeure
• 英文别名: 4-Dodecoxy-2-hydroxybenzoic acid
• CAS: 86841-00-1
• 化学式: C₁₉H₃₀O₄
• 分子量: 322.445
• InChiKey: QPOOMDFMBUZOQS-UHFFFAOYSA-N

物化性质

• 熔点：
  101-103 °C(Solv: ethanol (64-17-5); water (7732-18-5))
• 沸点：
  459.3±30.0 °C(Predicted)
• 密度：
  1.053±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  23
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-Hydroxy-4-n-dodecoxybenzoesaeure 、 乙二胺 在 1,2-diaminoethane dihydrochloride 、 对甲苯磺酸 作用下， 以 乙二醇 为溶剂， 反应 4.0h， 以60%的产率得到2-(4-Dodecoxy-2-hydroxyphenyl)-Δ²-imidazolin
  参考文献：
  名称：

  Beger, J.; Wagner, G.; Dinjus, U., Journal fur praktische Chemie (Leipzig 1954), 1983, vol. 325, # 2, p. 211 - 224

  摘要：

  DOI：
• 作为产物：
  描述：

  2,4-二羟基苯甲酸甲酯 在 sodium hydroxide 、 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 27.0h， 生成 2-Hydroxy-4-n-dodecoxybenzoesaeure
  参考文献：
  名称：

  Beger, J.; Wagner, G.; Uhlig, E., Journal fur praktische Chemie (Leipzig 1954), 1983, vol. 325, # 5, p. 708 - 718

  摘要：

  DOI：

文献信息

• Recording materials
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0219302A2

  公开（公告）日：1987-04-22

  A recording material contains an electron donating leuco dye and, as an electron accepting compound, a salicylic acid derivative having an alkyl group, an alkoxy group or an aryloxy group as a substituent or a metal salt thereof. The recording material has good color developability, working preservability and stability.

  一种记录材料含有一种电子供体白兰地染料，以及作为电子受体化合物的水杨酸衍生物（其取代基为烷基、烷氧基或芳氧基）或其金属盐。这种记录材料具有良好的显色性、工作保存性和稳定性。
• Photopolymerizable composition and recording material
  申请人：Fuji Photo Film Co., Ltd.

  公开号：EP1298490A2

  公开（公告）日：2003-04-02

  The present invention provides a photopolymerizable composition containing a polymerizable compound having an ethylenically unsaturated bond, a compound represented by the following general formula (I), and a radical generating agent capable of generating a radical by interacting with the compound represented by the following general formula (I). General Formula (I); In the general formula (I), R1, R2, and R3 each individually represent a hydrogen atom or a monovalent substituent; R4 represents at least one member selected from the group consisting of: a hydrogen atom, an aliphatic group, an aromatic group, and a heterocyclic group; Z1 represents a substituent necessary for allowing the compound represented by the general formula (I) to become a dye; and X- represents a group capable of forming an anion. The invention also provides a recording material in which a recording layer containing the photopolymerizable composition is provided on a support.

  本发明提供了一种可光聚合组合物，该组合物含有一种具有乙烯不饱和键的可聚合化合物、一种由以下通式(I)表示的化合物，以及一种能够通过与以下通式(I)表示的化合物相互作用而生成自由基的自由基生成剂。通式（I）； 在通式（I）中，R1、R2 和 R3 分别代表氢原子或一价取代基；R4 代表至少一个选自氢原子、脂肪族基团、芳香族基团和杂环基团的成员；Z1 代表使通式（I）所代表的化合物成为染料所必需的取代基；X- 代表能够形成阴离子的基团。本发明还提供了一种记录材料，在该记录材料中，含有可光聚合组合物的记录层被设置在支持物上。
• Method of screening compounds interacting with proteins of the p53 family
  申请人：Pfizer Products Inc.

  公开号：EP1480042A2

  公开（公告）日：2004-11-24

  There is provided a method for screening an organic non-peptide compound for interaction with one or more domains of either a wild-type human protein of the p53 family or a mutant human protein of the p53 family, which interaction can stabilize a functional conformation thereof under physiological conditions and promote wild-type activity of the protein of the p53 family, or restore wild-type activity to a mutant protein of the p53 family, which method comprises contacting said human protein of the p53 family, or one or more domains thereof, and said organic non-peptide compound, and monitoring the interaction thereof.

  提供了一种筛选有机非肽化合物与 p53 家族野生型人类蛋白质或 p53 家族突变型人类蛋白质的一个或多个结构域相互作用的方法，这种相互作用可在生理条件下稳定其功能构象，促进 p53 家族蛋白质的野生型活性，或恢复 p53 家族突变型蛋白质的野生型活性，该方法包括将所述 p53 家族人类蛋白质或其一个或多个结构域与所述有机非肽化合物接触，并监测其相互作用。
• HEAT-SENSITIVE RECORDING MATERIAL
  申请人：Fuji Photo Film Co., Ltd.

  公开号：EP1466751A1

  公开（公告）日：2004-10-13

  (A) The invention discloses a thermosensitive recording material comprising: a support; and a thermosensitive recording layer formed on the support, the thermosensitive recording layer containing an electron-donating colorless dye and an electron-accepting compound which develops color upon a reaction with the electron-donating colorless dye, wherein the thermosensitive recording material satisfies at least one of the following conditions (1) to (3). (1) an image density when thermal printing is performed from a side, of the support, having the thermosensitive recording layer with printing energy of 15.2 mJ/mm2 is 1.20 or more, and the thermosensitive recording material is used for a recording device having a printing speed of 10 cm/sec or more; (2) the thermosensitive recording material contains a sensitizer comprising at least one compound selected from the group consisting of 2-benzyloxynaphthalene, dimethylbenzyloxalate, m-terphenyl, ethyleneglycol tolyl ether, p-benzyl biphenyl, 1,2-diphenoxymethyl benzene, diphenyl sulfone and 1,2-diphenoxy ethane, and the image density after the thermosensitive recording material is brought into contact with a heat source of 70°C for 5 seconds is 0.15 or less; (3) the electron-accepting compound is a compound represented by the following Formula (1) Formula (1)R1-Ph-SO2R2   wherein R1 represents a hydroxyl group or an alkyl group, R2 represents -Ph, -NH-Ph, -Ph-OR3 or -NH-CO-NH-Ph, R3 represents an alkyl group, Ph represents a phenyl group and may be substituted with a substituent containing -SO2R2, and a volume-averaged grain size of the electron-donating colorless dye and electron-accepting compound is in a range of 0.5 to 1.0 µm. (B) A thermosensitive recording material comprises a thermosensitive recording layer containing an electron-donating colorless dye, an electron-accepting compound which develops color upon a reaction with the electron-donating colorless dye and a sensitizer, wherein the thermosensitive recording material satisfies at least one of the following conditions (1) to (3). (1) An image density when thermal printing is performed with a printing energy is 1.20 or more, and the thermosensitive recording material is used for a recording device having a printing speed of 10 cm/sec or more. (2) An image density after the thermosensitive recording material is brought into contact with a heat source of 70°C for 5 seconds is 0.15 or less, and the sensitizer is 2-benzyloxynaphthalene or the like. (3) the electron-accepting compound is a compound represented by R1-Ph-SO2R2 wherein R1 represents a hydroxyl group or an alkyl group, R2 represents -Ph, -NH-Ph, -Ph-OR3 or -NH-CO-NH-Ph, R3 represents an alkyl group, Ph represents a phenyl group and may be substituted with a substituent containing SO2R2, and a volume-averaged grain size is in a range of 0.5 to 1.0 µm.

  (A) 本发明公开了一种热敏记录材料，包括：支撑物；和形成在支撑物上的热敏记录层，该热敏记录层含有电子捐赠无色染料和电子接受化合物，该电子接受化合物与电子捐赠无色染料反应后显色，其中热敏记录材料至少满足以下条件（1）至（3）中的一个。 (1) 当从具有热敏记录层的支撑物的一侧进行热打印时，打印能量为 15.2 mJ/mm2 的图像密度为 1.20 或以上，且热敏记录材料用于打印速度为 10 厘米/秒或以上的记录设备； (2) 热敏记录材料含有敏化剂，该敏化剂包含至少一种选自以下组别的化合物：2-苄氧基萘、二甲基苄氧基萘、间三联苯、乙二醇对二甲苯醚、对苄基联苯、1,2-二苯氧基甲基苯、二苯砜和 1,2-二苯氧基乙烷，且热敏记录材料与 70°C 的热源接触 5 秒钟后的图像密度为 0.15 或更低； (3) 电子接受化合物是由下式表示的化合物 式(1) 式(1)R1-Ph-SO2R2 其中 R1 代表羟基或烷基，R2 代表-Ph、-NH-Ph、-Ph-OR3 或-NH-CO-NH-Ph，R3 代表烷基，Ph 代表苯基并可被含有-SO2R2 的取代基取代，且电子氖型无色染料和电子接受化合物的体积平均粒度在 0.5至1.0微米。 (B) 一种热敏记录材料，它包括一个热敏记录层，该层含有一种电子致性无色染料、一种电子受体化合物，该化合物在与电子致性无色染料和敏化剂反应后显色，其中热敏记录材料至少满足下列条件(1)至(3)之一。 (1) 当使用打印能量进行热打印时，图像密度为 1.20 或以上，且热敏记录材料用于打印速度为 10 厘米/秒或以上的记录设备。 (2) 热敏记录材料与 70°C 的热源接触 5 秒后的图像密度为 0.15 或更低，且敏化剂为 2-苄氧基萘或类似物。 (3) 电子接受化合物是由 R1-Ph-SO2R2 所代表的化合物，其中 R1 代表羟基或烷基，R2 代表-Ph、-NH-Ph、-Ph-OR3 或-NH-CO-NH-Ph，R3 代表烷基，Ph 代表苯基并可被含有 SO2R2 的取代基取代，且体积平均粒度在 0.5 至 1.0 微米范围内。
• RESIN-ADDITIVE MASTERBATCH
  申请人：Adeka Corporation

  公开号：EP2578620A1

  公开（公告）日：2013-04-10

  The present invention provides a resin additive masterbatch which not only is capable of containing a resin additive having a low melting point at a high concentration, but also can be continuously produced without strand breakage and has an improved surface tackiness. The resin additive masterbatch comprises, with respect to 100 parts by mass of (A) a crystalline resin, 100 to 900 parts by mass of (B) a resin additive, 0.1 to 10 parts by mass of (C) a metal salt of an organic acid other than fatty acid and 0.1 to 10 parts by mass of (D) a gelling agent, the resin additive masterbatch being characterized in that the above-described (B) resin additive retains a liquid state when melted with heating to 250°C and then cooled to 80°C and kept for 30 minutes.

  本发明提供了一种树脂添加剂母料，它不仅能在高浓度下含有低熔点的树脂添加剂， 而且能连续生产而不会断股，并具有更好的表面粘性。 该树脂添加剂母料包括（A）结晶树脂 100 至 900 份（按重量计）、（B）树脂添加剂 100 至 900 份（按重量计）、（C）脂肪酸以外的有机酸金属盐 0.1 至 10 份（按重量计）和（D）胶凝剂 0.1 至 10 份（按重量计）、 该树脂添加剂母料的特点是，上述（B）树脂添加剂在加热熔化至 250℃，然后冷却至 80℃并保持 30 分钟后，仍保持液态。