(1,2 and 4,5)-diepoxy-1-isopropyl-4-methylcyclohexane | 17023-73-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环己烷
• 英文名称: (1,2 and 4,5)-diepoxy-1-isopropyl-4-methylcyclohexane
• 英文别名: 1,2,4,5-diepoxy-p-menthane；1,2;4,5-diepoxy-p-menthane；1,2;4,5-Diepoxy-p-menthan；gamma-terpinene diepoxide；terpinene dioxide；1,2-4,5-Diepoxy-p-menthan；cis-1,2:4,5-Diepoxy-p-Menthane；1-methyl-5-propan-2-yl-4,8-dioxatricyclo[5.1.0.03,5]octane
• CAS: 17023-73-3
• 化学式: C₁₀H₁₆O₂
• 分子量: 168.236
• InChiKey: OMOHWPSXOIJOKA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  25.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  γ-松油烯 在 过氧化氢苯甲酰 、 氯仿 作用下， 生成 (1,2 and 4,5)-diepoxy-1-isopropyl-4-methylcyclohexane
  参考文献：
  名称：

  Richter; Presting, Chemische Berichte, 1931, vol. 64, p. 878,882

  摘要：

  DOI：

文献信息

• METHOD FOR MANUFACTURING AN EPOXY COMPOUND AND METHOD FOR EPOXIDIZING A CARBON-CARBON DOUBLE BOND
  申请人：Takumi Kiyoshi

  公开号：US20120108830A1

  公开（公告）日：2012-05-03

  The present invention provides a method for producing an epoxy compound, comprising oxidizing a carbon-carbon double bond of an organic compound by hydrogen peroxide in the presence of a neutral inorganic salt and a mixed catalyst of a tungsten compound (a), at least one phosphorus compound selected from the group consisting of phosphoric acids, phosphonic acids, and salts thereof (b) and a surfactant (c), and an epoxidizing method comprising oxidizing a carbon-carbon double bond by hydrogen peroxide in the presence of the catalyst and the neutral inorganic salt.

  本发明提供了一种生产环氧化合物的方法，包括在中性无机盐和钨化合物（a）、磷酸、膦酸及其盐（b）和表面活性剂（c）的混合催化剂存在下，通过过氧化氢氧化有机化合物的碳-碳双键，以及一种环氧化方法，包括在催化剂和中性无机盐存在下，通过过氧化氢氧化碳-碳双键。
• Oxetane polymers and methods of preparation thereof
  申请人：RENSSELAER POLYTECHNIC INSTITUTE

  公开号：US10377855B2

  公开（公告）日：2019-08-13

  The invention is directed to processes for preparation of oxetane polymers, wherein an epoxide accelerant is reacted with one or more equivalents of a 3-monosubstituted oxetane or a 3,3-disubstituted oxetane, wherein the epoxide accelerant is selected from the group consisting of 2,2-substituted epoxide, 2,2,3-substituted epoxide, 2,2,3,3-substituted epoxide, and mixtures thereof. Also disclosed are oxetane polymers prepared by the processes of the invention.

  本发明涉及制备氧杂环丁烷聚合物的工艺，其中环氧化物促进剂与一种或多种当量的3-单取代氧杂环丁烷或3,3-二取代氧杂环丁烷反应，其中环氧化物促进剂选自由2,2-取代环氧化物、2,2,3-取代环氧化物、2,2,3,3-取代环氧化物及其混合物组成的组。还公开了通过本发明工艺制备的氧杂环丁烷聚合物。
• Selective Oxidation of Monoterpenes with Hydrogen Peroxide Catalyzed by Peroxotungstophosphate (PCWP)
  作者：Satoshi Sakaguchi、Yutaka Nishiyama、Yasutaka Ishii

  DOI：10.1021/jo960275q

  日期：1996.1.1

  Catalytic epoxidation of monoterpenes with aqueous hydrogen peroxide catalyzed by peroxotung-stophosphate (PCWP) under biphase conditions using chloroform as the solvent was examined. A variety of terpenes was oxidized to the corresponding monoepoxides or diepoxides in good yields under mild conditions. For example, limonene (1) was converted into limonene oxide (la) in which the cyclohexene double bond was selectively epoxidized in almost quantitative yield. The oxidation of gamma-terpinene (2) with 2.2 equiv of 35% H2O2 took place with high stereoselectivity to give cis-diepoxide 2c. In terpenes bearing electron-withdrawing groups such as neryl acetate (3), geranyl acetate (4), citral (5), and geranyl nitrile (6), the double bonds remote from the substituents were epoxidized in preference to the others. The epoxidation of linalool (9) by the present catalyst-oxidant system produced the cyclic products, hydroxy furan 9a and hydroxy pyran 9b, rather than epoxide. tert-Butyl alcohol was successfully employed as the solvent by treating a hydrogen peroxide solution of tert-butyl alcohol with MgSO4 prior to use. The regioselectivities in the epoxidation of monoterpenes can be favorably explained from the electron densities of the double bonds which were estimated using the CAChe system.
• Richter; Wolff, Chemische Berichte, 1930, vol. 63, p. 1714,1719
  作者：Richter、Wolff

  DOI：——

  日期：——
• Elgendy, Eman M, Bollettino Chimico Farmaceutico, 2004, vol. 143, # 9, p. 337 - 339
  作者：Elgendy, Eman M

  DOI：——

  日期：——