Human Menopausal Gonadotrophin

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Human Menopausal Gonadotrophin
• 英文别名: 6,6-dimethylheptanal
• 化学式: C₉H₁₈O
• 分子量: 142.241
• InChiKey: CBUWTGCATVNMJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  、 、 2,5,5-Trimethylhexanal 、 4-(1',1'-dimethylethyl)pentanal 、 Human Menopausal Gonadotrophin 生成 、 7-甲基辛酸
  参考文献：
  名称：

  Method for Producing Isononanoic Acids from 2-Ethyl Hexanol

  摘要：

  从2-乙基己醇制备异壬酸的过程，其特点在于：(a)在催化剂的存在下，将2-乙基己醇脱水成辛烯；(b)在元素周期表第VIII族的过渡金属化合物的存在下，将步骤a)得到的辛烯与一氧化碳和氢反应，生成异壬醛；(c)将步骤b)得到的异壬醛氧化成异壬酸。

  公开号：

  US20150191410A1
• 作为产物：
  描述：

  3,3-二甲基-1-丁烯 在 acetylacetonatodicarbonylrhodium(l) 亚磷酸三苯酯 、 (R,S)-binaphos 、 氢气 作用下， 以 苯 为溶剂， 50.0~60.0 ℃ 、10.13 MPa 条件下， 反应 49.0h， 生成 Human Menopausal Gonadotrophin
  参考文献：
  名称：

  Asymmetric hydroformylation catalyzed by an Rh(I)-(R, S)-BINAPHOS complex: substituent effects in olefins on the regioselectivity

  摘要：

  Olefins bearing the larger substituents at the allylic position were hydroformylated in the higher iso/normal selectivity when Rh(I)-(R,S)-BINAPHOS was used as a catalyst. Deuterioformylation of 4,4,4-triphenyl-1-butene suggests that the higher iso/normal ratio may be attributed to the accelerated CO insertion to the iso-alkylrhodium 7i.

  DOI：

  10.1016/s0022-328x(96)06620-x

文献信息

• Method for Producing Isononanoic Acid Esters, Starting from 2-Ethyl Hexanol
  申请人：Oxea GmbH

  公开号：US20150158805A1

  公开（公告）日：2015-06-11

  A Process for preparing carboxylic esters of a mixture of structurally branched C9 monocarboxylic acids proceeding from 2-ethylhexanol is characterized in that (a) 2-ethylhexanol is dehydrated to an octene mixture in the presence of a catalyst; (b) the octene mixture obtained in step a) is reacted in the presence of a transition metal compound of group VIII of the periodic table of the elements with carbon monoxide and hydrogen to give a mixture of isomeric isononanals; (c) the mixture of isomeric isononanals obtained in step b) is oxidized to a mixture of structurally branched C9 monocarboxylic acids; and (d) the mixture of structurally branched C9 monocarboxylic acids obtained in step c) is reacted with alcohols to give carboxylic esters.

  一种制备从2-乙基己醇出发的结构分支C9单羧酸酯混合物的方法，其特征在于 (a) 在催化剂存在下，将2-乙基己醇脱水成为辛烯混合物； (b) 在步骤a)中获得的辛烯混合物在元素周期表第VIII族的过渡金属化合物存在下与一氧化碳和氢反应，得到异辛醛的混合物； (c) 在步骤b)中获得的异辛醛混合物被氧化成结构分支的C9单羧酸的混合物；以及 (d) 在步骤c)中获得的结构分支C9单羧酸混合物与醇反应，得到羧酸酯。
• HETEROCYCLIC TRPV1 RECEPTOR LIGANDS
  申请人：Tafesse Laykea

  公开号：US20100137306A1

  公开（公告）日：2010-06-03

  The invention relates to compounds of formulae I(a)-I(d): and pharmaceutically acceptable derivatives thereof, compositions comprising an effective amount of a compound of formulae I(a)-I(d) or a pharmaceutically acceptable derivative thereof, and methods for treating or preventing a condition such as pain, UI, an ulcer, IBD and IBS, comprising administering to an animal in need thereof an effective amount of a compound of formulae I(a)-I(d) or a pharmaceutically acceptable derivative thereof.

  该发明涉及以下化合物的化学式：I(a)-I(d)，及其药学上可接受的衍生物，包括含有化合物I(a)-I(d)或其药学上可接受的衍生物的有效量的组合物，以及用于治疗或预防疼痛、尿失禁、溃疡、炎症性肠病和肠易激综合征等疾病的方法，包括向需要的动物施用化合物I(a)-I(d)或其药学上可接受的衍生物的有效量。
• Isononylamines from 2-Ethylhexanol, Processes for Their Preparation, and Their Use
  申请人：Oxea GmbH

  公开号：US20150152023A1

  公开（公告）日：2015-06-04

  Process for preparing isononylamines starting out from 2-ethylhexanol, characterized in that (a) 2-ethylhexanol is dehydrated in the presence of a catalyst to form octene; (b) the octene obtained in step a) is reacted with carbon monoxide and hydrogen in the presence of a transition metal compound of group VIII of the Periodic Table of the Elements to form isononanal; and (c) the isononanal obtained in step b) is converted into isononylamines.

  从2-乙基己醇开始制备异壬胺的过程，其特征在于(a) 在催化剂的存在下将2-乙基己醇脱水形成辛烯；(b) 在步骤a)中获得的辛烯与一周期表第VIII族过渡金属化合物存在下与一氧化碳和氢反应形成异壬醛；(c) 在步骤b)中获得的异壬醛转化为异壬胺。
• Vinyl Esters of Isononanoic Acid Starting from 2-Ethyl Hexanol, Methods for the Production Thereof and Use Thereof
  申请人：Oxea Gmbh

  公开号：US20150166456A1

  公开（公告）日：2015-06-18

  Process for preparing the vinyl ester of isononanoic acid starting out from 2-ethylhexanol, characterized in that (a) 2-ethylhexanol is dehydrated in the presence of a catalyst to form octene; (b) the octene obtained in step a) is converted into an isononanoic acid having one more carbon atom; and (c) the isononanoic acid obtained in step b) is converted into the corresponding vinyl ester.

  从2-乙基己醇开始制备异壬酸乙烯酯的过程，其特征在于(a)在催化剂的存在下，将2-乙基己醇脱水形成辛烯；(b)将步骤(a)中获得的辛烯转化为具有一个碳原子的异壬酸；(c)将步骤(b)中获得的异壬酸转化为相应的乙烯酯。
• Piperidine derivatives
  申请人：SANKYO COMPANY LIMITED

  公开号：EP0583971A1

  公开（公告）日：1994-02-23

  Compounds of formula (I): wherein:    R represents H or a mono- or poly- carboxylic acyl group;    R¹ represents H or a carboxylic ester moiety;    R² represents an alkyl group, an alkenyl group, an alkynyl group, an aryl group, or an aralkyl group, said groups being optionally substituted, or R² represents a carboxylic ester moiety;    n = 1 - 4;    Y is O or S;    and esters thereof,    are useful as heat and photo- stabilisers for polymeric materials.

  式(I)的化合物：其中：R代表H或单酰基或多酰基群；R¹代表H或羧酸酯基；R²代表烷基、烯基、炔基、芳基或芳基烷基，这些基团可选择性地被取代，或者R²代表羧酸酯基；n = 1 - 4；Y为O或S；及其酯，可用作聚合材料的热稳定剂和光稳定剂。