2-Isobutylidene-malonic acid diisopropyl ester | 69246-90-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Isobutylidene-malonic acid diisopropyl ester
• 英文别名: Dipropan-2-yl 2-(2-methylpropylidene)propanedioate；dipropan-2-yl 2-(2-methylpropylidene)propanedioate
• CAS: 69246-90-8
• 化学式: C₁₃H₂₂O₄
• 分子量: 242.315
• InChiKey: NVYQFTBOMRNUKB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.69
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-Isobutylidene-malonic acid diisopropyl ester 在 N-溴代丁二酰亚胺(NBS) 、 过氧化苯甲酰 作用下， 以 四氯化碳 为溶剂， 生成 2-(2-Bromo-2-methyl-propylidene)-malonic acid diisopropyl ester
  参考文献：
  名称：

  Kristensen,J. et al., Bulletin des Societes Chimiques Belges, 1978, vol. 87, p. 721 - 732

  摘要：

  DOI：
• 作为产物：
  描述：

  丙二酸二异丙酯 、 异丁醛 在 titanium(IV) isopropylate 、 四氯化钛 、 三乙胺 、 呋喃 作用下， 以 二氯甲烷 为溶剂， 生成 2-Isobutylidene-malonic acid diisopropyl ester
  参考文献：
  名称：

  多组分反应研究：Ti（IV）衍生物促进米色型三分子缩合反应

  摘要：

  我们已经开发出Ti（IV）/ Et 3 N促进的芳香族杂环（呋喃，吡咯，咪唑，吲哚）与醛和活性亚甲基化合物的三分子缩合。在吲哚和乙酰乙酸甲酯的情况下，根据反应条件，反应得到三组分产物或三环环戊[ b ]吲哚衍生物。在这两种情况下，NMR分析都表明烯醇钛是反应中涉及的反应性物质。

  DOI：

  10.1016/j.tet.2010.02.025

文献信息

• Process for producing ethylene oligomers
  申请人：HANWHA TOTAL PETROCHEMICAL CO., LTD.

  公开号：US10308563B2

  公开（公告）日：2019-06-04

  The present disclosure relates to a process for producing ethylene oligomers and more particularly, to a process for oligomerizing ethylene by recycling butene, hexene, and octene in an ethylene oligomerization reaction with a catalyst system including a transition metal or transition metal precursor, a ligand with a backbone structure expressed by the following Chemical Formula 1, and a co-catalyst. [Chemical Formula 1] R1—O—Y—O—R2 or R1—OC(═O)—Y—C(═O)OR2 Herein, R1, R2 are each independently hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl, or substituted heterohydrocarbyl, and Y represents a group connecting O or C(═O)O and is hydrocarbyl, substituted hydrocarbyl, hetero hydrocarbyl, or substituted heterohydrocarbyl. According to the oligomerization method of the present disclosure, in the distribution of the produced α-olefins, C10″-C12″ α-olefins care highly distributed, the produced α-olefins have a remarkably high purity.

  本公开涉及一种生产乙烯低聚物的工艺，更具体地说，涉及一种通过在乙烯低聚反应中回收丁烯、己烯和辛烯而使乙烯低聚的工艺，该催化剂体系包括过渡金属或过渡金属前体、具有以下化学式1表示的骨架结构的配位体和助催化剂。[化学式 1] R1-O-Y-O-R2 或 R1-OC(═O)-Y-C(═O)OR2 这里，R1、R2 各自独立地为烃基、取代的烃基、杂烃基或取代的杂烃基，Y 代表连接 O 或 C(═O)O 的基团，并且是烃基、取代的烃基、杂烃基或取代的杂烃基。根据本公开的低聚方法，在生成的α-烯烃的分布中，C10″-C12″ α-烯烃的分布较多，生成的α-烯烃具有显著的高纯度。
• PROCESS FOR PRODUCING ETHYLENE OLIGOMERS
  申请人：HANWHA TOTAL PETROCHEMICAL CO., LTD.

  公开号：US20180170827A1

  公开（公告）日：2018-06-21

  The present disclosure relates to a process for producing ethylene oligomers and more particularly, to a process for oligomerizing ethylene by recycling butene, hexene, and octene in an ethylene oligomerization reaction with a catalyst system including a transition metal or transition metal precursor, a ligand with a backbone structure expressed by the following Chemical Formula 1, and a co-catalyst. [Chemical Formula 1] R 1 —O—Y—O—R 2 or R 1 —OC(═O)—Y—C(═O)OR 2 Herein, R 1 , R 2 are each independently hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl, or substituted heterohydrocarbyl, and Y represents a group connecting O or C(═O)O and is hydrocarbyl, substituted hydrocarbyl, hetero hydrocarbyl, or substituted heterohydrocarbyl. According to the oligomerization method of the present disclosure, in the distribution of the produced α-olefins, C10″-C12″ α-olefins care highly distributed, the produced α-olefins have a remarkably high purity.
• CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME
  申请人：HANWHA TOTAL PETROCHEMICAL CO., LTD.

  公开号：US20180169642A1

  公开（公告）日：2018-06-21

  The present disclosure relates to a catalyst system for ethylene oligomerization and a method for producing ethylene oligomerization using the same and more particularly, to a catalyst system for ethylene oligomerization including a transition metal or transition metal precursor with a new structure, a ligand with a backbone structure expressed by the following Chemical Formula 1 or Chemical Formula 2, and a co-catalyst for providing an ethylene oligomer and a method for producing ethylene oligomerization using the same. [Chemical Formula 1] R 1 —OC(═O)—Y 1 —C(═O)OR 2 Herein, R 1 , R 2 are each independently hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl, or substituted heterohydrocarbyl, and Y 1 represents a group connecting CO(═O). [Chemical Formula 2] R 1 —O—Y 2 —O—R 2 Herein, R 1 , R 2 are each independently hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl, or substituted heterohydrocarbyl, and Y 2 represents a group connecting O and is a linear, branched, or cyclic alkyl group having 3 or more carbon atoms, or hetero hydrocarbyl, or substituted heterohydrocarbyl. The catalyst system of the present disclosure has an excellent catalytic activity and in the distribution of the produced α-olefins, C8″-C18″ α-olefins are highly distributed.
• Multicomponent reactions studies: Yonemitsu-type trimolecular condensations promoted by Ti(IV) derivatives
  作者：Stéphane Gérard、Andrea Renzetti、Bérangère Lefevre、Antonella Fontana、Paolo de Maria、Janos Sapi

  DOI：10.1016/j.tet.2010.02.025

  日期：2010.4

  We have developed a Ti(IV)/Et3N-promoted trimolecular condensation of aromatic heterocycles (furan, pyrrole, imidazole, indole) with aldehydes and active methylene compounds. In the case of indole and methyl acetoacetate the reaction afforded three-component products or tricyclic cyclopenta[b]indole derivative, depending on the reaction conditions. In both cases, NMR analysis evidenced that titanium

  我们已经开发出Ti（IV）/ Et 3 N促进的芳香族杂环（呋喃，吡咯，咪唑，吲哚）与醛和活性亚甲基化合物的三分子缩合。在吲哚和乙酰乙酸甲酯的情况下，根据反应条件，反应得到三组分产物或三环环戊[ b ]吲哚衍生物。在这两种情况下，NMR分析都表明烯醇钛是反应中涉及的反应性物质。
• Kristensen,J. et al., Bulletin des Societes Chimiques Belges, 1978, vol. 87, p. 721 - 732
  作者：Kristensen,J. et al.

  DOI：——

  日期：——