5,10,15-trioxanonadecan-1-ol | 143429-31-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5,10,15-trioxanonadecan-1-ol
• 英文别名: 4-[4-(4-Butoxybutoxy)butoxy]butan-1-ol
• CAS: 143429-31-6
• 化学式: C₁₆H₃₄O₄
• 分子量: 290.444
• InChiKey: PHBABHQZDDRAQW-UHFFFAOYSA-N

物化性质

• 沸点：
  383.1±37.0 °C(Predicted)
• 密度：
  0.939±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  20
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  5,10,15-trioxanonadecan-1-ol 在 硫酸 作用下， 以 1,4-二氧六环 为溶剂， 反应 20.0h， 生成 {4-[4-(4-Butoxy-butoxy)-butoxy]-butoxy}-acetic acid ethyl ester
  参考文献：
  名称：

  Artificial non-peptide single ion channels

  摘要：

  We report the synthesis of amphiphilic molecules composed of glycolate ethers of monoalkyloligo(1,4-butylene glycol) complexed with dioctadecyldimethylammonium cation. When inserted into a bilayer lipid membrane, these molecules exhibited several properties characteristic of single ion channels. Stable and constant conductance levels were observed, with transitions between open and closed states at a millisecond to second range. The conductance levels were on the order of 10(1)-10(3) pS, and the channels were classified into three types on the basis of their conductances and gating properties. The channels were cation selective over anion by a factor of approximately 5. In channels having the largest conductance, reversible and repeatable inactivation occurred with transmembrane voltages greater than 70 mV, while the other types of channels did not show voltage-dependent gating. We tentatively interpret these single ion channel properties to result from the formation of a molecular aggregate wherein the polar oligoether-carboxylates are covered with the hydrophobic alkyl groups of the ammonium in the bilayer membrane.

  DOI：

  10.1021/ja00046a002
• 作为产物：
  描述：

  正溴丁烷 、 5,10-dioxa-tetradecane-1,14-diol 在 sodium hydride 作用下， 生成 5,10,15-trioxanonadecan-1-ol
  参考文献：
  名称：

  Artificial non-peptide single ion channels

  摘要：

  We report the synthesis of amphiphilic molecules composed of glycolate ethers of monoalkyloligo(1,4-butylene glycol) complexed with dioctadecyldimethylammonium cation. When inserted into a bilayer lipid membrane, these molecules exhibited several properties characteristic of single ion channels. Stable and constant conductance levels were observed, with transitions between open and closed states at a millisecond to second range. The conductance levels were on the order of 10(1)-10(3) pS, and the channels were classified into three types on the basis of their conductances and gating properties. The channels were cation selective over anion by a factor of approximately 5. In channels having the largest conductance, reversible and repeatable inactivation occurred with transmembrane voltages greater than 70 mV, while the other types of channels did not show voltage-dependent gating. We tentatively interpret these single ion channel properties to result from the formation of a molecular aggregate wherein the polar oligoether-carboxylates are covered with the hydrophobic alkyl groups of the ammonium in the bilayer membrane.

  DOI：

  10.1021/ja00046a002

文献信息

• [DE] IMIDAZOLIUM-METHYLSULFITE ALS AUSGANGSVERBINDUNGEN ZUR HERSTELLUNG IONISCHER FLÜSSIGKEITEN<br/>[EN] IMIDAZOLIUM-METHYL SULFITES FOR USE AS STARTING COMPOUNDS FOR PRODUCING IONIC LIQUIDS<br/>[FR] SULFITES D'IMIDAZOLIUM-METHYLE UTILISES COMME COMPOSES DE DEPART AUSGANGSVERBINDUNGEN POUR LA PRODUCTION DE LIQUIDES IONIQUES
  申请人：BASF AG

  公开号：WO2006021303A1

  公开（公告）日：2006-03-02

  Imidazolium-methylsulfite der allgemeinen Formel (I), in der die Reste unabhängig voneinander folgende Bedeutung haben: R1 bis R3: Wasserstoff, Halogen, Hydroxy, Amino, Aminocarbonyl, Sulfo, Cyano, Nitro; C1- bis C20-Alkyl, C2- bis C20-Alkenyl, C2- bis C20-Alkinyl, C1- bis C20-Alkyloxy, C2- bis C20-Alkenyloxy, C2- bis C20-Alkinyloxy, C1- bis C20-Alkylcarbonyl, C1- bis C20-Alkyloxycarbonyl, C1- bis C20-Acyloxy, C1- bis C20-Alkylaminocarbonyl, Di-(C1- bis C20-Alkyl)amino-carbonyl, C1- bis C20-Alkylamino, Di-(C1- bis C20-alkyl)amino, C1- bis C20-Alkylsulfonyl, C3- bis C8-Cycloalkyl, wobei die genannten Alkyl-, Alkenyl-, Alkinyl- und Cycloalkyl-Gruppen substituiert und/oder CH2-Gruppen durch Sauerstoff ersetzt sein können; Phenyl, Phenoxy, wobei diese ihrerseits substituiert sein können; R4: Sulfo; C1- bis C20-Alkyl, C2- bis C20-Alkenyl, C2- bis C20-Alkinyl, C3- bis C8-Cycloalkyl, wobei die genannten Alkyl-, Alkenyl-, Alkinyl- und Cycloalkyl-Gruppen substituiert und/oder CH2-Gruppen durch Sauerstoff ersetzt sein können; Phenyl, wobei dieses substituiert sein kann; oder R1 zusammen mit R4, und/oder R2 zusammen mit R3, oder R4 zusammen mit R2: Alkylen -(CH2)n- mit n = 4, 5 oder 6 oder Butadienylen -CH = CH-CH = CH-, wobei diese substituiert und/oder CH2-Gruppen durch Sauerstoff und CH-Gruppen durch NR5 ersetzt sein können.

  Imidazolium-甲磺酸酯的通式（I），其中残基独立地具有以下含义：R1至R3：氢，卤素，羟基，氨基，氨基羰基，磺酰基，氰基，硝基；C1至C20-烷基，C2至C20-烯基，C2至C20-炔基，C1至C20-烷氧基，C2至C20-烯氧基，C2至C20-炔氧基，C1至C20-烷基羰基，C1至C20-烷氧羰基，C1至C20-酰氧基，C1至C20-烷基氨基羰基，二（C1至C20-烷基）氨基羰基，C1至C20-烷基氨基，二（C1至C20-烷基）氨基，C1至C20-烷基磺酰基，C3至C8-环烷基，其中上述烷基，烯基，炔基和环烷基基团可以被取代和/或CH2基团可以被氧原子取代；苯基，苯氧基，它们本身可以被取代；R4：磺酰基；C1至C20-烷基，C2至C20-烯基，C2至C20-炔基，C3至C8-环烷基，其中上述烷基，烯基，炔基和环烷基基团可以被取代和/或CH2基团可以被氧原子取代；苯基，它可以被取代；或R1与R4一起，和/或R2与R3一起，或R4与R2一起：亚烷基-(CH2)n-其中n = 4, 5或6或丁二烯基-CH = CH-CH = CH-，其中这些可以被取代和/或CH2基团可以被氧原子取代和CH基团可以被NR5取代。
• Imidazolium-Methyl Sulfites for Use as Starting Compounds for Producing Ionic Liquids
  申请人：Szarvas Laszlo

  公开号：US20070255064A1

  公开（公告）日：2007-11-01

  Imidazolium methylsulfites of the general formula (I) where the radicals have, independently of one another, the following meanings: R 1 to R 3 : hydrogen, halogen, hydroxy, amino, aminocarbonyl, sulfo, cyano, nitro; C 1 -C 20 -alkyl, C 2 -C 20 -alkenyl, C 2 -C 20 -alkynyl, C 1 -C 20 -alkyloxy, C 2 -C 20 -alkenyloxy, C 2 -C 20 -alkynyloxy, C 1 -C 20 -alkylcarbonyl, C 1 -C 20 -alkyloxycarbonyl, C 1 -C 20 -acyloxy, C 1 -C 20 -alkylaminocarbonyl, di(C 1 -C 20 -alkyl)aminocarbonyl, C 1 -C 20 -alkylamino, di(C 1 -C 20 -alkyl)amino, C 1 -C 20 -alkylsulfonyl, C 3 -C 8 -cycloalkyl, where the alkyl, alkenyl, alkynyl and cycloalkyl groups mentioned can be substituted and/or have their CH 2 groups replaced by oxygen; phenyl, phenoxy, where these can in turn be substituted; R 4 : sulfo; C 1 -C 20 -alkyl, C 2 -C 20 -alkenyl, C 2 -C 20 -alkynyl, C 3 -C 8 -cycloalkyl, where the alkyl, alkenyl, alkynyl and cycloalkyl groups mentioned can be substituted and/or have their CH 2 groups replaced by oxygen; phenyl, where this can be substituted; or R 1 together with R 4 , and/or R 2 together with R 3 , or R 4 together with R 2 : alkylene —(CH 2 ) n — where n=4, 5 or 6 or butadienylene —CH═CH—CH═CH—, where these can be substituted and/or have the CH 2 groups replaced by oxygen and the CH groups replaced by NR 5 .

  通式（I）的咪唑甲基亚磺酸盐，其中基团独立地具有以下含义：R1至R3：氢、卤素、羟基、氨基、氨基甲酰、磺酰、氰基、硝基；C1-C20烷基、C2-C20烯基、C2-C20炔基、C1-C20烷氧基、C2-C20烯氧基、C2-C20炔氧基、C1-C20烷基羰基、C1-C20烷氧羰基、C1-C20酰氧基、C1-C20烷基氨基甲酰、二（C1-C20烷基）氨基甲酰、C1-C20烷基氨基、二（C1-C20烷基）氨基、C1-C20烷基磺酰基、C3-C8环烷基，其中所述的烷基、烯基、炔基和环烷基可以被取代和/或其CH2基团被氧取代；苯基、苯氧基，其中这些可以被取代；R4：磺酰基；C1-C20烷基、C2-C20烯基、C2-C20炔基、C3-C8环烷基，其中所述的烷基、烯基、炔基和环烷基可以被取代和/或其CH2基团被氧取代；苯基，其中这可以被取代；或者R1和R4、R2和R3、或R4和R2一起：烷基链—（CH2）n—，其中n = 4、5或6或丁二烯基链—CH═CH—CH═CH—，其中这些可以被取代和/或其CH2基团被氧取代，CH基团被NR5取代。
• Controlled rate of foam breakage in hard surface cleaners
  申请人：Ecolab USA, Inc.

  公开号：US10975333B2

  公开（公告）日：2021-04-13

  The present invention relates to mildly alkaline bathroom and/or hard surface cleaners providing improved foam performance. In particular, a concentrated, preferably disinfecting, high performance foaming cleaning composition is disclosed which can reduce or eliminate the need for scrubbing on bathroom and other hard surfaces. Methods of use are further disclosed for bathroom and/or other hard surface cleaning. The foam has increased stability for a period of time, followed by dissipation with an audible “crackling” sound and easy rinsability.

  本发明涉及可改善泡沫性能的弱碱性浴室和/或硬表面清洁剂。特别是，本发明公开了一种浓缩型、优选消毒型、高性能发泡清洁组合物，可减少或消除对浴室和其他硬表面的擦洗需要。还进一步公开了浴室和/或其他硬表面清洁的使用方法。泡沫在一段时间内稳定性增强，随后消散并发出 "噼啪 "声，易于冲洗。
• IMIDAZOLIUM-METHYLSULFITE ALS AUSGANGSVERBINDUNGEN ZUR HERSTELLUNG IONISCHER FLÜSSIGKEITEN
  申请人：BASF Aktiengesellschaft

  公开号：EP1786780A1

  公开（公告）日：2007-05-23
• VERFAHREN ZUR CHLORIERUNG VON ALKOHOLEN
  申请人：BASF SE

  公开号：EP1928811B1

  公开（公告）日：2008-12-31