3-(4-fluorophenyl)benzo[f]quinoline | 28707-36-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3-(4-fluorophenyl)benzo[f]quinoline
• CAS: 28707-36-0
• 化学式: C₁₉H₁₂FN
• 分子量: 273.309
• InChiKey: MHVIIBWXJKXPJG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  碳酸亚乙烯酯 、 2-p-Fluorobenzylideneaminonaphthalene 在 dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer 作用下， 以 异丙醇 为溶剂， 反应 12.0h， 以71%的产率得到3-(4-fluorophenyl)benzo[f]quinoline
  参考文献：
  名称：

  铑催化N-芳基甲亚胺与碳酸亚乙烯酯脱氢环化合成喹啉

  摘要：

  在这里，我们报告了一种新的 Rh 催化的N-芳基甲亚胺的 C-H/C-H 烯基化，其中碳酸亚乙烯酯作为亚乙烯基单元。C3,C4-非取代喹啉的 40 个例子是从可商购的起始材料中获得的。这一确定的工艺具有极其简单的系统、较低的催化剂负载量以及生物活性分子后功能化的能力。

  DOI：

  10.1021/acs.orglett.1c03231

文献信息

• Efficient and Highly Selective Method for the Synthesis of Benzo(naphtho)quinoline Derivatives Catalyzed by Iodine
  作者：Xiang-Shan Wang、Jie Zhou、Ming-Yue Yin、Ke Yang、Shu-Jiang Tu

  DOI：10.1021/cc900165j

  日期：2010.3.8

  A mild, efficient, and highly selective method for the synthesis of pyranoquinoline and furoquinoline derivatives via a three-component reaction of aromatic aldehyde, naphthalen-2-amine or anthracen-2-amine and 2,3-dihydrofuran, or 3,4-dihydro-2H-pyran catalyzed by iodine is described. It should be noted that exo-isomer was obtained with high selectivity in good yields, which was confirmed by X-ray

  通过芳族醛，萘-2-胺或蒽-2-胺与2,3-二氢呋喃或3,4-的三组分反应合成吡喃喹啉和呋喃喹啉衍生物的温和，高效且高度选择性的方法描述了碘催化的二氢-2H-吡喃。应当指出，通过X-射线衍射分析证实了以高收率以高选择性获得外型-异构体。当使用链正丁基乙烯基醚作为反应物时，高收率地分离出了3-芳基苯并（石脑油）[f]喹啉，但是丁氧基的意外损失。
• Deaminative Cyclization of Tertiary Amines for the Synthesis of 2-Arylquinoline Derivatives with a Nonsubstituted Vinylene Fragment
  作者：Qinghe Gao、Yimei Guo、Zhenhua Sun、Xiaodan He、Yiqiao Gao、Guangping Fan、Penghui Cao、Lizhen Fang、Suping Bai、Yanlong Jia

  DOI：10.1021/acs.orglett.2c03904

  日期：2023.1.13

  regioselective synthesis of β,γ-nonsubstituted 2-arylquinolines from aldehydes and arylamines has been accomplished. The deaminative cyclization is also extended to long-chain tertiary alkylamines, enabling diverse alkyl groups to be concurrently installed into the pyridine rings. This process demonstrates a new conversion pathway for the simultaneous dual C(sp3)–H bond functionalization of tertiary amines, wherein

  以三乙胺为亚乙烯基源，完成了从醛和芳基胺区域选择性合成 β,γ-未取代的 2-芳基喹啉的便捷方案。脱氨基环化也扩展到长链叔烷基胺，使不同的烷基能够同时安装到吡啶环上。该过程展示了叔胺同时双 C(sp 3 )–H 键功能化的新转化途径，其中原位生成的瞬态无环烯胺经历 Povarov 反应。
• Organic metal complex, and organic light emitting device and display apparatus using the same
  申请人：SAMSUNG ELECTRONICS CO., LTD.

  公开号：US10367156B2

  公开（公告）日：2019-07-30

  Provided is an organic metal complex having a structure represented by the following general formula (1): MLmL′n  (1) where: M represents a metal atom selected from Ir, Pt, Rh, Os, and Zn; L and L′, which are different from each other, each represent a bidentate ligand; m represents an integer of 1 to 3 and n represents an integer of 0 to 2, provided that m+n is 3; a partial structure MLm represents a structure represented by the following general formula (2): and a partial structure ML′n represents a structure including a monovalent bidentate ligand.

  本发明提供了一种具有以下通式 (1) 所代表结构的有机金属络合物： MLmL′n (1) 其中M 代表选自 Ir、Pt、Rh、Os 和 Zn 的金属原子；L 和 L′互不相同，各自代表双齿配体；m 代表 1 至 3 的整数，n 代表 0 至 2 的整数，条件是 m+n 为 3；部分结构 MLm 代表由以下通式（2）表示的结构： 而局部结构 ML′n 表示包括一价双叉配体的结构。
• ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME
  申请人：Kamatani Jun

  公开号：US20100219407A1

  公开（公告）日：2010-09-02

  Provided is an organic metal complex having a structure represented by the following general formula (1): ML m L′ n (1) where: M represents a metal atom selected from Ir, Pt, Rh, Os, and Zn; L and L′, which are different from each other, each represent a bidentate ligand; m represents an integer of 1 to 3 and n represents an integer of 0 to 2, provided that m+n is 3; a partial structure ML m represents a structure represented by the following general formula (2): and a partial structure ML′ n represents a structure including a monovalent bidentate ligand.
• US9554442B2
  申请人：——

  公开号：US9554442B2

  公开（公告）日：2017-01-24