1,2-dichloro-2-propoxyethane | 339984-86-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,2-dichloro-2-propoxyethane
• 英文别名: 1-(1,2-Dichloroethoxy)propane
• CAS: 339984-86-0
• 化学式: C₅H₁₀Cl₂O
• mdl: MFCD19233941
• 分子量: 157.04
• InChiKey: UNRFKVIECRVZQQ-UHFFFAOYSA-N

物化性质

• 沸点：
  172.7±20.0 °C(Predicted)
• 密度：
  1.117±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  8
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,2-dichloro-2-propoxyethane 在 fluorine 、 sodium fluoride 作用下， 以 1,1,2-三氯三氟乙烷（CFC-113） 、 苯 为溶剂， -10.0~20.0 ℃ 、120.0 kPa 条件下， 以40%的产率得到全氟丙基1,2-二氯三氟乙醚
  参考文献：
  名称：

  摘要：

  Perfluoro(2-propoxypropionyl) fluoride (1a), which is the precursor of the perfluorinated propyl vinyl ether (PPVE) monomer of an industrially important perfluoroalkoxy copolymer (PFA), was synthesized by utilizing direct fluorination of the non-fluorinated counterpart for the first time. The partially-fluorinated ester 7 synthesized from the desired perfluorinated acid fluoride la itself and the non-fluorinated alcohol 5, which has a carbon skeleton corresponding to the desired compound 1a, was perfluorinated by liquid-phase direct fluorination with elemental fluorine. Degradation of the resulting perfluorinated ester 8 gave 2 mols of the desired acid fluoride 1a. In a sense, this process can be called self-multiplication of a perfluorinated acid fluoride from a non-fluorinated alcohol.

  DOI：

  10.1002/1615-4169(20010226)343:2<215::aid-adsc215>3.3.co;2-z
• 作为产物：
  描述：

  正丙基乙烯基醚 在 氯 作用下， 以 二氯甲烷 为溶剂， 生成 1,2-dichloro-2-propoxyethane
  参考文献：
  名称：

  Shellhamer, Dale F.; Allen, Jeannette L.; Allen, Rachel D., Journal of Organic Chemistry, 2003, vol. 68, # 10, p. 3932 - 3937

  摘要：

  DOI：

文献信息

• Shellhamer, Dale F.; Allen, Jeannette L.; Allen, Rachel D., Journal of Organic Chemistry, 2003, vol. 68, # 10, p. 3932 - 3937
  作者：Shellhamer, Dale F.、Allen, Jeannette L.、Allen, Rachel D.、Gleason, David C.、Schlosser, Colleen O'Neil、Powers, Benjamin J.、Probst, John W.、Rhodes, Michelle C.、Ryan, Andrew J.、Titterington, Peter K.、Vaughan, Gregory Gawayne、Heasley, Victor L.

  DOI：——

  日期：——
• ——
  作者：Takashi Okazoe、Kunio Watanabe、Masahiro Itoh、Daisuke Shirakawa、Hidenobu Murofushi、Hidekazu Okamoto、Shin Tatematsu

  DOI：10.1002/1615-4169(20010226)343:2<215::aid-adsc215>3.3.co;2-z

  日期：2001.2.26

  Perfluoro(2-propoxypropionyl) fluoride (1a), which is the precursor of the perfluorinated propyl vinyl ether (PPVE) monomer of an industrially important perfluoroalkoxy copolymer (PFA), was synthesized by utilizing direct fluorination of the non-fluorinated counterpart for the first time. The partially-fluorinated ester 7 synthesized from the desired perfluorinated acid fluoride la itself and the non-fluorinated alcohol 5, which has a carbon skeleton corresponding to the desired compound 1a, was perfluorinated by liquid-phase direct fluorination with elemental fluorine. Degradation of the resulting perfluorinated ester 8 gave 2 mols of the desired acid fluoride 1a. In a sense, this process can be called self-multiplication of a perfluorinated acid fluoride from a non-fluorinated alcohol.