9-oxodecanal | 36218-85-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 9-oxodecanal
• 英文别名: 10-Oxodecanon
• CAS: 36218-85-6
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.252
• InChiKey: NNWIRQZPEDSHLN-UHFFFAOYSA-N

物化性质

• 沸点：
  277.1±23.0 °C(Predicted)
• 密度：
  0.905±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  12
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  9-oxodecanal 在 锰 、 水 、 2,4,6-collidine hydrochloride 作用下， 以 四氢呋喃 为溶剂， 以85%的产率得到10-hydroxydecan-2-one
  参考文献：
  名称：

  Mn(0)-Mediated Chemoselective Reduction of Aldehydes. Application to the Synthesis of α-Deuterioalcohols

  摘要：

  A mild simple safe chemoselective reduction of different kinds to the corresponding alcohols mediated by the Mn dust/water system is described. In addition to this, the use of D2O leads to the synthesis of alpha-deuerated alcohols and constitutes an efficient inexpensive alternative for the preparation of these compounds.

  DOI：

  10.1021/jo1015618
• 作为产物：
  描述：

  10-hydroxydecan-2-one 在 aluminum oxide 作用下， 生成 9-oxodecanal
  参考文献：
  名称：

  Cottier,L.; Descotes,G., Bulletin de la Societe Chimique de France, 1972, p. 1072 - 1076

  摘要：

  DOI：

文献信息

• Electrochemical Wacker Type Reaction with a Double Mediatory System Consisting of Palladium Complex and Tri(4-bromophenyl)amine
  作者：Tsutomu Inokuchi、Liu Ping、Fumihiro Hamaue、Miyoko Izawa、Sigeru Torii

  DOI：10.1246/cl.1994.121

  日期：1994.1

  The electrochemical Wacker type oxidation of terminal olefins by using palladium chloride or palladium acetate and tri(4-bromophenyl)amine as a recyclable mediator in either a divided cell or an undivided cell afforded the corressponding methyl ketones in good yields.

  终端烯烃的电化学瓦克型氧化通过使用氯化钯或醋酸钯及三(4-溴苯基)胺作为可回收的介体，在分隔池或非分隔池中获得了相应的甲基酮，产率良好。
• SYNTHESIS OF OMEGA-AMINO CARBOXYLIC ACIDS AND THEIR ESTERS FROM UNSATURATED FATTY ACID DERIVATIVES
  申请人：Hannen Peter

  公开号：US20130165685A1

  公开（公告）日：2013-06-27

  The invention relates to a process for preparing omega-amino acids or their esters, which is characterized by the following steps: c) ozonolysis of unsaturated fatty acids or fatty acid derivatives, d) reductive amination of the reaction mixture obtained from the reaction with ozone, to give the omega-amino acid or ester thereof, the reaction being carried out with a C 1 -C 5 alcohol in a mixture with at least 0.5% by weight of water as solvent, based on the total amount of solvent.

  本发明涉及一种制备ω-氨基酸或其酯的方法，其特征在于以下步骤：c）臭氧化不饱和脂肪酸或脂肪酸衍生物，d）还原胺化臭氧反应所得的反应混合物，以得到ω-氨基酸或其酯，该反应在C1-C5醇与至少0.5重量％的水的混合物中进行，作为溶剂，基于溶剂总量。
• Processes for the preparation of indolopyrrolocarbazole derivatives
  申请人：BANYU PHARMACEUTICAL CO., LTD.

  公开号：EP1264836A1

  公开（公告）日：2002-12-11

  This invention relates to processes for the preparation of intermediates which are useful in the synthesis of compounds of the general formula or pharmaceutically salts thereof, wherein R1 and R2 each represent an OH group, R1 is located at the 1- or 2-position, R2 is located at the 10- or 11-position, R2 is located at the 11-position when R1 is located at the 1-position, and R2 is located at the 10-position when R1 is located at the 2-position. The compounds of the present invention have an excellent antitumor effect and are hence useful as antitumor agents in the field of medicine.

  本发明涉及用于合成通式化合物或其药用盐的中间体的制备工艺。 或其药用盐，其中 R1 和 R2 各代表一个 OH 基团，R1 位于 1 位或 2 位，R2 位于 10 位或 11 位，当 R1 位于 1 位时 R2 位于 11 位，当 R1 位于 2 位时 R2 位于 10 位。 本发明的化合物具有极佳的抗肿瘤效果，因此在医药领域可用作抗肿瘤剂。
• Self-Assembled Bidentate Ligands for Ru-Catalyzedanti-Markovnikov Hydration of Terminal Alkynes
  作者：Floris Chevallier、Bernhard Breit

  DOI：10.1002/anie.200503826

  日期：2006.2.27
• Complexes of technetium-99m with alkylene amine oximes
  申请人：AMERSHAM INTERNATIONAL plc

  公开号：EP0123504B1

  公开（公告）日：1989-09-20