3-ethyl-4-methyl-5-hexen-3-ol | 25201-42-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-ethyl-4-methyl-5-hexen-3-ol
• 英文别名: 3-ethyl-4-methylhex-5-en-3-ol
• CAS: 25201-42-7
• 化学式: C₉H₁₈O
• 分子量: 142.241
• InChiKey: OWVSKEMVERUIDK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3-ethyl-4-methyl-5-hexen-3-ol 生成 Diaethyl-γ-methallylcarbinol
  参考文献：
  名称：

  Reversible Grignard and organolithium reactions

  摘要：

  DOI：

  10.1021/ja00475a026
• 作为产物：
  描述：

  crotyltetrabutylstiborane 、 3-戊酮 在 AlCl₃ etherate 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 以75%的产率得到3-ethyl-4-methyl-5-hexen-3-ol
  参考文献：
  名称：

  Studies of the synthetic applications of element-organic compounds of 15th and 16th Groups. 97. Pentaorganylstiborane. 2. Reactions of pentaorganylstiboranes with acyl chlorides and ketones

  摘要：

  DOI：

  10.1021/jo00028a075

文献信息

• Iron-Catalyzed Electrochemical Allylation of Carbonyl Compounds by Allylic Acetates
  作者：Muriel Durandetti、Clotilde Meignein、Jacques Périchon

  DOI：10.1021/jo026782r

  日期：2003.4.1

  synthesized from aldehydes or ketones and allylic acetates, using an electrochemical process catalyzed by iron complexes. We first studied the reactivity of allyl acetate, using N,N-dimethylformamide (DMF) or acetonitrile (AN) as solvent, FeBr(2) as catalyst, and Fe as the sacrificial anode. Then we tested the regioreactivity of crotyl acetate and other allylic derivatives.

  使用铁络合物催化的电化学过程，由醛或酮与乙酸烯丙酯合成均烯丙基醇。我们首先研究了乙酸烯丙酯的反应性，使用N，N-二甲基甲酰胺（DMF）或乙腈（AN）作为溶剂，FeBr（2）作为催化剂，Fe作为牺牲阳极。然后，我们测试了巴豆乙酸盐和其他烯丙基衍生物的区域反应性。
• Electrogenerated zinc as the catalyst in the allylation of carbonyl compounds direct synthesis of α-methylene-γ-lactones
  作者：Y. Rollin、S. Derien、E. Duñach、C. Gebehenne、J. Perichon

  DOI：10.1016/s0040-4020(01)87246-x

  日期：1993.8

  The electroreduction of a catalytic amount of ZnBr2 in acetonitrile provided a active Zn*, able to catalyze the reductive coupling of allyl bromides and chlorides with carbonyl compounds with high regioselectivity. Substituted α-methylene γ-lactones were obtained from functionalized allyl derivatives.

  乙腈中催化量的ZnBr 2的电还原可提供活性Zn *，该催化剂能够以高区域选择性催化烯丙基溴和氯化物与羰基化合物的还原偶联。从官能化的烯丙基衍生物获得取代的α-亚甲基γ-内酯。
• Iron-catalyzed allylation of ketones
  作者：Muriel Durandetti、Jacques Périchon

  DOI：10.1016/j.tetlet.2006.06.134

  日期：2006.8

  Allylation of ketones has been efficiently performed using iron-complex catalysis and led to homoallylic alcohols in high yields. (c) 2006 Elsevier Ltd. All rights reserved.
• Direct transformation of allylic and benzylic alcohols or their silylated derivatives into organolithium compounds
  作者：Emma Alonso、David Guijarro、Miguel Yus

  DOI：10.1016/0040-4020(95)00709-h

  日期：1995.10

  The reaction of allylic or benzylic alcohols 1 with n-butyllithium followed by treatment with lithium powder and a catalytic amount of DTBB (5 mol %) in THF at room temperature gives a solution of the corresponding alkyllithium reagent, which reacts in situ with different electrophiles to yield the expected products 2. Alternatively, the O-silylated derivatives of the same alcohols are lithiated under Barbier-type reaction conditions to afford the same reaction products with better yields.
• BENKESER R. A.; SIKLOSI M. P.; MOZDZEN E. C., J. AMER. CHEM. SOC., 1978, 100 17 2134-2139
  作者：BENKESER R. A.、 SIKLOSI M. P.、 MOZDZEN E. C.

  DOI：——

  日期：——