4-epi-11-nor-aristola-1(10),11-diene

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: 4-epi-11-nor-aristola-1(10),11-diene
• 英文别名: (1aS,7R,7aS,7bR)-7,7a-dimethyl-1-methylidene-2,3,5,6,7,7b-hexahydro-1aH-cyclopropa[a]naphthalene
• 化学式: C₁₄H₂₀
• 分子量: 188.313
• InChiKey: DDBCGKCAUYNHJO-WBMYTEFPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  4-epi-11-nor-aristola-1(10),11-diene 在 palladium on activated charcoal 氢气 作用下， 生成 (1aR,7R,7aR,7bS)-1,7,7a-Trimethyl-decahydro-cyclopropa[a]naphthalene
  参考文献：
  名称：

  Sesquiterpene constituents from the liverwort Bazzania japonica

  摘要：

  The hydrodistillation products of the liverwort Bazzania japonica were separated by preparative gas chromatography (GC) and investigated by spectroscopic methods. Seven unknown compounds were isolated and identified by GC-MS and NMR. Four of them, the norsesquiterpene hydrocarbons 4-epi-11-nor-aristola-1(10), 11-diene (1), 4-epi-11-nor-aristola-1,9,11-triene (2), 4-epi-11-nor-aristola-9. 11-diene (3), and one oxygenated sesquiterpene, (-)-aristol-1(10)-en-12-ol (5) are new natural compounds, and one, (+)-himachala-2.4-diene (7). has for the first time been isolated from liverworts. The absolute configurations of 5 and 7 were derived by chemical correlation reactions and/or enantioselective GC using cyclodextrin phases. 1, 2 and 3 have identical absolute configuration. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(03)00188-2

文献信息

• Sesquiterpene constituents from the liverwort Bazzania japonica
  作者：Runhua Lu、Claudia Paul、Simla Basar、Wilfried A König、Toshihiro Hashimoto、Yoshinori Asakawa

  DOI：10.1016/s0031-9422(03)00188-2

  日期：2003.7

  The hydrodistillation products of the liverwort Bazzania japonica were separated by preparative gas chromatography (GC) and investigated by spectroscopic methods. Seven unknown compounds were isolated and identified by GC-MS and NMR. Four of them, the norsesquiterpene hydrocarbons 4-epi-11-nor-aristola-1(10), 11-diene (1), 4-epi-11-nor-aristola-1,9,11-triene (2), 4-epi-11-nor-aristola-9. 11-diene (3), and one oxygenated sesquiterpene, (-)-aristol-1(10)-en-12-ol (5) are new natural compounds, and one, (+)-himachala-2.4-diene (7). has for the first time been isolated from liverworts. The absolute configurations of 5 and 7 were derived by chemical correlation reactions and/or enantioselective GC using cyclodextrin phases. 1, 2 and 3 have identical absolute configuration. (C) 2003 Elsevier Science Ltd. All rights reserved.

表征谱图