Chemo- and stereoselective reduction of (pivaloyloxy)methyl 6,6-dihalopenicillanates by trineophyltin hydride: Selective synthesis of 6β-halopenicillanates
作者:Ernesto G. Mata、Oreste A. Mascaretti、Adriana E. Zuñiga、Alicia B. Chopa、Julio C. Podestá
DOI:10.1016/s0040-4039(00)99280-3
日期:1989.1
A new Triorganotin hydride, Trineophyltin hydride was prepared and its chemo- and stereoselectivity towards reduction of Pom 6,6-homo- and hetero- dihalopenicillanates was examined. The trineophyltin hydride reveals higher stereoselectivity compared to that by tributyltin hydride at 25°C.
制备了一种新的三有机锡氢化物,三氢叶绿素氢化物,并研究了其对还原Pom 6,6-同型和异二卤代黄花酸酯的化学和立体选择性。与三丁基锡氢化物在25°C时相比,氢化三叶新素具有更高的立体选择性。