2,3-Dimethoxy-5-phenylbenzo[i]phenanthridine | 1196959-07-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2,3-Dimethoxy-5-phenylbenzo[i]phenanthridine
• CAS: 1196959-07-5
• 化学式: C₂₅H₁₉NO₂
• 分子量: 365.431
• InChiKey: TUASJTZDFURUIS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  28
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  31.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  、 2-氨基苯乙烯 以 乙腈 为溶剂， 以76%的产率得到2,3-Dimethoxy-5-phenylbenzo[i]phenanthridine
  参考文献：
  名称：

  Construction of Multiring Frameworks by Metal-Free Cascade Reactions of Stable Isochromenylium Tetrafluoroborate

  摘要：

  Efficient methodologies for constructing several multiring frameworks have been developed utilizing the cascade reactions of air-stable isochromenylium tetrafluoroborates with olefins. Successive additions of two equivalents of styrene-type olefins to isochromenylium tetrafluoroborate (ICTB) I have been observed and their mechanisms were proposed and discussed. Intramolecular capture of the early stage cat ionic intermediates by predevised heteroatoms or Friedel-Crafts donors provided two different types of bridged-ring systems.

  DOI：

  10.1021/jo902051g

文献信息

• Construction of Multiring Frameworks by Metal-Free Cascade Reactions of Stable Isochromenylium Tetrafluoroborate
  作者：Zhi-Long Hu、Wen-Jian Qian、Sheng Wang、Shaozhong Wang、Zhu-Jun Yao

  DOI：10.1021/jo902051g

  日期：2009.11.20

  Efficient methodologies for constructing several multiring frameworks have been developed utilizing the cascade reactions of air-stable isochromenylium tetrafluoroborates with olefins. Successive additions of two equivalents of styrene-type olefins to isochromenylium tetrafluoroborate (ICTB) I have been observed and their mechanisms were proposed and discussed. Intramolecular capture of the early stage cat ionic intermediates by predevised heteroatoms or Friedel-Crafts donors provided two different types of bridged-ring systems.