(Z)-ethyl 3-phenyl-3-(4-pyridazinyl)propenoate | 139938-10-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (Z)-ethyl 3-phenyl-3-(4-pyridazinyl)propenoate
• 英文别名: ethyl (Z)-3-phenyl-3-pyridazin-4-ylprop-2-enoate
• CAS: 139938-10-6
• 化学式: C₁₅H₁₄N₂O₂
• 分子量: 254.288
• InChiKey: KWDMKGGYWWDZOW-UVTDQMKNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  52.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  磷酰基乙酸三乙酯 、 4-Benzoylpyridazine 在 sodium hydride 作用下， 生成 (Z)-ethyl 3-phenyl-3-(4-pyridazinyl)propenoate
  参考文献：
  名称：

  Pyridazines, LVIII: 1-Phenyl-1-pyridazinyl-2-substituted ethenes, synthesis and configuration

  摘要：

  Starting from phenyl pyridazinyl ketones 1 and 3 various 1-phenyl 1-pyridazinyl-2-substituted ethenes (2 a-c, 4, 5 a, b, 6 a, b, 7-9) were prepared by Wittig-Horner- oder Wittig-type reactions. Configurational assignments of these novel compounds were achieved by NOE difference spectroscopy.

  DOI：

  10.1007/bf00811114

文献信息

• Pyridazines, LVIII: 1-Phenyl-1-pyridazinyl-2-substituted ethenes, synthesis and configuration
  作者：Gottfried Heinisch、Wolfgang Holzer、Thierry Huber

  DOI：10.1007/bf00811114

  日期：1991.12

  Starting from phenyl pyridazinyl ketones 1 and 3 various 1-phenyl 1-pyridazinyl-2-substituted ethenes (2 a-c, 4, 5 a, b, 6 a, b, 7-9) were prepared by Wittig-Horner- oder Wittig-type reactions. Configurational assignments of these novel compounds were achieved by NOE difference spectroscopy.