3-[1-(tert-butoxycarbonyl)-2-methyl-1H-indol-3-yl]-N-butyl-4-(2-methyl-1-benzothiophen-3-yl)maleimide | 894428-76-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 3-[1-(tert-butoxycarbonyl)-2-methyl-1H-indol-3-yl]-N-butyl-4-(2-methyl-1-benzothiophen-3-yl)maleimide
• 英文别名: Tert-butyl 3-[1-butyl-4-(2-methyl-1-benzothiophen-3-yl)-2,5-dioxopyrrol-3-yl]-2-methylindole-1-carboxylate；tert-butyl 3-[1-butyl-4-(2-methyl-1-benzothiophen-3-yl)-2,5-dioxopyrrol-3-yl]-2-methylindole-1-carboxylate
• CAS: 894428-76-3
• 化学式: C₃₁H₃₂N₂O₄S
• 分子量: 528.672
• InChiKey: QFURUXKJDCLSHS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  38
• 可旋转键数：
  7
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  96.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3-[1-(tert-butoxycarbonyl)-2-methyl-1H-indol-3-yl]-N-butyl-4-(2-methyl-1-benzothiophen-3-yl)maleimide 在 正丁胺 作用下， 反应 4.0h， 以80%的产率得到N-butyl-3-(2-methyl-1-benzothiophen-3-yl)-4-(2-methyl-1H-indol-3-yl)maleimide
  参考文献：
  名称：

  A convenient synthesis of 3,4-diaryl(hetaryl)-substituted maleimides and maleic anhydrides

  摘要：

  A convenient procedure has been developed for the synthesis of 3,4-diaryl(or hetaryl)maleimides by cross coupling of N-substituted 3,4-dibromomaleimides with aryl(hetaryl)boronic acids in the presence of Pd(Ph3P)(4) and CsF The reaction ensures high yields of the products and requires relatively small amount of the catalyst; it can be performed on an enlarged scale. The resulting maleimides are readily converted into the corresponding maleic anhydrides.

  DOI：

  10.1134/s1070428006100162
• 作为产物：
  描述：

  N-正丁基马来酰亚胺 在 4-二甲氨基吡啶 、 四(三苯基膦)钯 、 溴 、 sodium acetate 、 cesium fluoride 、 lithium hexamethyldisilazane 作用下， 以 四氢呋喃 、 1,4-二氧六环 、 溶剂黄146 为溶剂， 反应 9.25h， 生成 3-[1-(tert-butoxycarbonyl)-2-methyl-1H-indol-3-yl]-N-butyl-4-(2-methyl-1-benzothiophen-3-yl)maleimide
  参考文献：
  名称：

  A convenient synthesis of 3,4-diaryl(hetaryl)-substituted maleimides and maleic anhydrides

  摘要：

  A convenient procedure has been developed for the synthesis of 3,4-diaryl(or hetaryl)maleimides by cross coupling of N-substituted 3,4-dibromomaleimides with aryl(hetaryl)boronic acids in the presence of Pd(Ph3P)(4) and CsF The reaction ensures high yields of the products and requires relatively small amount of the catalyst; it can be performed on an enlarged scale. The resulting maleimides are readily converted into the corresponding maleic anhydrides.

  DOI：

  10.1134/s1070428006100162

文献信息

• Thermally irreversible organic photochromic compounds for optical memory
  作者：V. A. Barachevsky、Yu. P. Strokach、Yu. A. Puankov、M. M. Krayushkin

  DOI：10.1002/poc.1191

  日期：2007.11

  some photochromic compounds (58 diarylethenes and 9 fulgimides), the results of our spectral and kinetic studies are presented. Aiming at targeted synthesis of new photochromic compounds, the structure – photochromic behavior relationship (SPBR) for the synthesized compounds has been analyzed. The perspectives for application of these compounds in development of recording media for use in optical memory

  对于某些光致变色化合物（58个双芳硫醚和9个全黄酰亚胺），我们给出了光谱和动力学研究的结果。为了有针对性地合成新的光致变色化合物，已经分析了合成化合物的结构-光致变色行为关系（SPBR）。概述了这些化合物在开发用于光学存储设备的记录介质中的应用前景。版权所有©2007 John Wiley＆Sons，Ltd.