(2-(Pyridin-2-yloxy)phenyl)methanamine | 655256-67-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2-(Pyridin-2-yloxy)phenyl)methanamine
• 英文别名: (2-pyridin-2-yloxyphenyl)methanamine
• CAS: 655256-67-0
• 化学式: C₁₂H₁₂N₂O
• mdl: MFCD03840017
• 分子量: 200.24
• InChiKey: DMJWPOGKCPDYGZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.083
• 拓扑面积：
  48.1
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS
  申请人：Bristol-Myers Squibb Company

  公开号：EP3580220B1

  公开（公告）日：2021-11-17
• [EN] FK228 ANALOGS AND METHODS OF MAKING AND USING THE SAME<br/>[FR] ANALOGUES DE FK228 ET METHODES DE PRODUCTION ET D'UTILISATION DESDITS ANALOGUES
  申请人：WISCONSIN ALUMNI RES FOUND

  公开号：WO2005058298A2

  公开（公告）日：2005-06-30

  The present invention provides FK228 analogs and methods of making and using the same. Such analogs are potent inhibitors of histone deacetylase and, in certain embodiments, are capable of specifically targeting cancerous cells and tissues. In preferred embodiments, these analogs are characterized by a cyclic disulfide design.