5-甲氧基己醛 | 10413-29-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 5-甲氧基己醛
• 英文名称: 5-methoxy-hexanal
• 英文别名: 5-Methoxyhexanal；5-methoxyhexanal
• CAS: 10413-29-3
• 化学式: C₇H₁₄O₂
• 分子量: 130.187
• InChiKey: BVLFDKFUHALDGW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  5-羟基己腈 在 sodium 作用下， 以 四氢呋喃 为溶剂， 生成 5-甲氧基己醛
  参考文献：
  名称：

  Colonge,J. et al., Bulletin de la Societe Chimique de France, 1966, p. 2005 - 2011

  摘要：

  DOI：

文献信息

• [EN] BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF<br/>[FR] COMPOSITIONS, COMPOSÉS BOLAAMPHIPHILES, ET LEURS UTILISATIONS
  申请人：LAUREN SCIENCES LLC

  公开号：WO2016168580A1

  公开（公告）日：2016-10-20

  Bolaamphiphilic compounds are provided according to formula (I); where HG1, HG2 and L1 are as defined herein. Provided bolaamphiphilic compounds and the pharmaceutical compositions thereof are useful for delivering GDNF or NGF into animal or human brain.

  根据公式（I），提供了双亲嵌段化合物；其中HG1、HG2和L1如本文所定义。提供的双亲嵌段化合物及其制成的药物组合物可用于将GDNF或NGF输送到动物或人类大脑中。
• INHIBITOR OF APOPTOSIS PROTEIN (IAP) ANTAGONISTS
  申请人：Sanford-Burnham Medical Research Institute

  公开号：US20150307499A1

  公开（公告）日：2015-10-29

  Provided herein are compounds that modulate the activity of inhibitor of apoptosis proteins (IAPs), compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.

  本文提供的是调节细胞凋亡抑制蛋白(IAPs)活性的化合物，包含这些化合物的组合物，以及使用这些化合物和组合物的方法。
• NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
  申请人：BP Corporation North America Inc.

  公开号：EP2115153B1

  公开（公告）日：2013-06-05
• Inhibitor of Apoptosis Protein (IAP) Antagonists
  申请人：Sanford-Burnham Medical Research Institute

  公开号：US20170081362A1

  公开（公告）日：2017-03-23

  Provided herein are compounds that modulate the activity of inhibitor of apoptosis proteins (IAPB), compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.
• Use of Inhibitor of Apoptosis Protein (IAP) Antagonists in HIV Therapy
  申请人：Sanford-Burnham Medical Research Institute

  公开号：US20170196879A1

  公开（公告）日：2017-07-13

  Provided herein is the use of compounds that modulate the activity of inhibitor of apoptosis proteins (1APs), alone or in combination with other therapeutic agents, in the treatment of human immunodeficiency virus (HIV). Described herein is the use of IAP antagonists in the treatment of human immunodeficiency virus (HIV) in a mammal, alone or in combination with other therapeutic agents used in HIV therapy. In one aspect, provided herein is a method of treating human immunodeficiency virus (HIV) in an individual in need thereof comprising administering a therapeutically effective amount of at least one inhibitor of apoptosis proteins (IAP) antagonist.