6,10-二甲基-5-十一碳烯-2-酮 | 689-66-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 6,10-二甲基-5-十一碳烯-2-酮
• 英文名称: 6,10-dimethyl-undec-5-en-2-one
• 英文别名: 3,4,9,10-tetrahydro-pseudoionone；6,10-Dimethyl-undec-5-en-2-on；6,10-dimethyl-5-undecen-2-one；6,10-dimethylundec-5-en-2-one
• CAS: 689-66-7
• 化学式: C₁₃H₂₄O
• 分子量: 196.333
• InChiKey: COFFUYZBRGBAQS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2914190090

反应信息

• 作为反应物：
  描述：

  6,10-二甲基-5-十一碳烯-2-酮 在 palladium on activated charcoal 作用下， 生成 六氢假紫罗酮
  参考文献：
  名称：

  Preparation of a higher aliphatic ketone

  摘要：

  公开号：

  US02783257A1
• 作为产物：
  描述：

  6-甲基-2-庚酮 在 Lindlar's catalyst 、 正己烷 、 氨 、 sodium methylate 、 Petroleum ether 作用下， 生成 6,10-二甲基-5-十一碳烯-2-酮
  参考文献：
  名称：

  合成的神经药醇和相关的C 15醇

  摘要：

  已经合成和表征了许多与神经甾醇有关的C 15醇。气相色谱法是分离顺反异构体的有效工具。

  DOI：

  10.1002/hlca.19590420729

文献信息

• [EN] NOVEL USE OF PHENYL PHOSPHINIC ACID<br/>[FR] NOUVELLE UTILISATION D'ACIDE PHÉNYLPHOSPHINIQUE
  申请人：DSM IP ASSETS BV

  公开号：WO2018091624A1

  公开（公告）日：2018-05-24

  The present invention is directed towards a process for the manufacture of gamma, delta-unsaturated ketones of the general formula (III) by reacting a tertiary vinyl carbinol of the general formula (I) with an isopropenyl alkyl ether of the general formula (II) in the presence of a catalyst of the general formula (IV), wherein R1 and R6 are independently from each other methyl or ethyl, R3 is methyl, and R2 is a saturated or unsaturated linear, branched or cyclic hydrocarbyl group with 1 to 46 C atoms. The present invention is also directed towards the reaction mixture as such, i.e. the mixture of the compound of formula (I), the compound of formula (II) and the catalyst of formula (IV).

  本发明涉及一种用于制备通式（III）的γ，δ-不饱和酮的方法，该方法通过将通式（I）的三级乙烯羟基化合物与通式（II）的异丙烯基醚在通式（IV）的催化剂存在下反应而得到，其中R1和R6分别独立为甲基或乙基，R3为甲基，R2为具有1至46个碳原子的饱和或不饱和线性、支链或环烃基。本发明还涉及反应混合物，即通式（I）化合物、通式（II）化合物和通式（IV）催化剂的混合物。
• Process for producing 6-methyl-3-hepten-2-one and 6-methyl-2-heptanone analogues, and process for producing phytone or isophytol
  申请人：Kuraray Co., Lyd.

  公开号：US06232506B1

  公开（公告）日：2001-05-15

  Provided are a process for producing 6-methyl-3-hepten-2-one by cross aldol condensation carried out while each continuously adding to acetone, isovaleraldehyde and an aqueous alkali containing an alkaline substance; a process for producing a 6-methyl-2-heptanone analogue represented by Formula (1): wherein n is an integer of 0 or 1 or more; which comprises allowing hydrogen, acetone and an aldehyde represented by Formula (2): wherein n is as defined above; X and Y each represents a hydrogen atom or they are coupled together to form a carbon-carbon bond; and Z and W each represents a hydrogen atom or they are coupled together to form a carbon-carbon bond; to react in the presence of an aqueous alkali containing an alkaline substance, and a hydrogenation catalyst; and a process for producing phytone or isophytol using the 6-methyl-3-hepten-2-one or the 6-methyl-2-heptanone analogue.

  提供一种制备6-甲基-3-庚烯-2-酮的方法，该方法通过交叉醛缩反应，在连续添加丙酮、异戊醛和含碱性物质的水性碱溶液的同时进行；一种制备由式（1）表示的6-甲基-2-庚酮类似物的方法，其中n是0或1或更多的整数；该方法包括在含碱性物质的水性碱溶液和氢化催化剂的存在下，使氢气、丙酮和由式（2）表示的醛反应，其中n如上所定义；X和Y分别表示氢原子或它们耦合形成碳-碳键；Z和W分别表示氢原子或它们耦合形成碳-碳键；以及一种使用6-甲基-3-庚烯-2-酮或6-甲基-2-庚酮类似物制备脂肪酸酯或异脂醇的方法。
• Process for producing 6-methyl-3-hepten-2-one and 6-methyl-2-heptanone
  申请人：Kuraray Co., Ltd.

  公开号：US05955636A1

  公开（公告）日：1999-09-21

  Provided are a process for producing 6-methyl-3-hepten-2-one by cross aldol condensation carried out while each continuously adding to acetone, isovaleraldehyde and an aqueous alkali containing an alkaline substance; a process for producing a 6-methyl-2-heptanone analogue represented by Formula (1): ##STR1## wherein n is an integer of 0 or 1 or more; which comprises allowing hydrogen, acetone and an aldehyde represented by Formula (2): ##STR2## wherein n is as defined above; X and Y each represents a hydrogen atom or they are coupled together to form a carbon-carbon bond; and Z and W each represents a hydrogen atom or they are coupled together to form a carbon-carbon bond; to react in the presence of an aqueous alkali containing an alkaline substance, and a hydrogenation catalyst; and a process for producing phyton or isophytol using the 6-methyl -3-hepten-2-one or the 6-methyl-2-heptanone analogue.

  提供了一种制备6-甲基-3-庚烯-2-酮的过程，该过程通过交叉醛缩反应，在持续添加丙酮、异戊醛和含有碱性物质的水溶性碱中进行；一种制备由公式（1）表示的6-甲基-2-庚酮类似物的过程：##STR1## 其中n是0或1或更多的整数；其中包括在水溶性碱和氢化催化剂的存在下，使氢、丙酮和由公式（2）表示的醛反应：##STR2## 其中n如上所定义；X和Y分别表示氢原子或它们耦合形成碳-碳键；Z和W分别表示氢原子或它们耦合形成碳-碳键；以及使用6-甲基-3-庚烯-2-酮或6-甲基-2-庚酮类似物制备萜烯或异萜醇的过程。
• USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINED ASYMMETRIC HYDROGENATIONS
  申请人：DSM IP ASSETS B.V.

  公开号：US20150321986A1

  公开（公告）日：2015-11-12

  The present invention relates to a process of manufacturing compound having stereogenic centres from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centres. The process involves two asymmetric hydrogenation steps. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.

  本发明涉及一种从具有丙型双键的不对称E/Z异构体混合物中制造具有立体异构中心的化合物的过程。氢化产物在立体异构中心处具有特定的所需构型。该过程涉及两个不对称的氢化步骤。该过程非常优越，因为它以高效的方式从起始产品的立体异构体混合物中形成所需的手性产物。
• USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINING ASYMMETRIC HYDROGENATION AND ISOMERIZATION
  申请人：DSM IP ASSETS B.V.

  公开号：US20160185702A1

  公开（公告）日：2016-06-30

  The present invention relates to a process of manufacturing compound having stereogenic centres from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centres. The process involves an asymmetric hydrogenation and an isomerization step. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.

  本发明涉及一种从具有原手性双键的不饱和化合物的E/Z异构体混合物中制造具有立体异构中心的化合物的过程。氢化产物在立体异构中心处具有特定的所需构型。该过程涉及不对称氢化和异构化步骤。该过程非常优越，因为它以高效的方式从起始产品的立体异构体混合物中形成所需的手性产物。