7,8-bis(dibromomethylene)tetradecane | 1003567-99-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 7,8-bis(dibromomethylene)tetradecane
• 英文别名: 7,8-Bis(dibromomethylidene)tetradecane；7,8-bis(dibromomethylidene)tetradecane
• CAS: 1003567-99-4
• 化学式: C₁₆H₂₆Br₄
• 分子量: 537.998
• InChiKey: UHLSJOFEWZGSAP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.8
• 重原子数：
  20
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  7,8-bis(dibromomethylene)tetradecane 在 叔丁基锂 作用下， 以 正己烷 为溶剂， 以61%的产率得到9-(dibromomethylene)pentadec-7-yne
  参考文献：
  名称：

  Synthesis of gem-dihaloenynes and butatrienes from gem-dihalovinyl derivatives

  摘要：

  gem-Dihaloenynes were synthesized in high yields from 1,1,4,4-tetrahalo-1,3-butadienes through the Fritsch-Buttenberg-Wiechell (FBW) rearrangement mediated by an organolithium compound. Butatriene derivatives could be obtained efficiently via an organolithium-mediated reaction of o-halo-(2,2-dihalovinyl)benzenes. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.06.060
• 作为产物：
  描述：

  trimethyl(oct-1-yn-1-yl)silane 在 dibutylbis(cyclopentadienyl)zirconium 、 溴 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 生成 7,8-bis(dibromomethylene)tetradecane
  参考文献：
  名称：

  Synthesis of gem-dihaloenynes and butatrienes from gem-dihalovinyl derivatives

  摘要：

  gem-Dihaloenynes were synthesized in high yields from 1,1,4,4-tetrahalo-1,3-butadienes through the Fritsch-Buttenberg-Wiechell (FBW) rearrangement mediated by an organolithium compound. Butatriene derivatives could be obtained efficiently via an organolithium-mediated reaction of o-halo-(2,2-dihalovinyl)benzenes. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.06.060

文献信息

• Synthesis of stereo-defined 1,1,4,4-tetrahalo- and 1,1,4,4-mixed-tetrahalo-1,3-butadienes
  作者：Hui-Jun Zhang、Zhiyi Song、Chao Wang、Christian Bruneau、Zhenfeng Xi

  DOI：10.1016/j.tetlet.2007.11.152

  日期：2008.1

  Stereo-defined 1,1,4,4-tetrahalo- and 1,1,4,4-mixed-tetrahalo-1,3-butadienes were obtained in excellent yields via desilylation-halogenation of their corresponding 1,4-bis(trimethylsilyl)-1,4-dihalo-1,3-dienes, which could be readily prepared from the zirconocene-mediated high-yield and high-regioselective cyclo-dimerization of 1-trimethylsilyl-1-alkynes followed by halogenation. These poly-functionalized gem-dihalodienes are potentially useful building blocks. (c) 2007 Elsevier Ltd. All rights reserved.
• Synthesis of gem-dihaloenynes and butatrienes from gem-dihalovinyl derivatives
  作者：Tianhao Meng、Hui-Jun Zhang、Zhenfeng Xi

  DOI：10.1016/j.tetlet.2012.06.060

  日期：2012.8

  gem-Dihaloenynes were synthesized in high yields from 1,1,4,4-tetrahalo-1,3-butadienes through the Fritsch-Buttenberg-Wiechell (FBW) rearrangement mediated by an organolithium compound. Butatriene derivatives could be obtained efficiently via an organolithium-mediated reaction of o-halo-(2,2-dihalovinyl)benzenes. (C) 2012 Elsevier Ltd. All rights reserved.