2-butoxythiazole | 69096-71-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-butoxythiazole
• 英文别名: 2-tert-butoxy-thiazole；2-[(2-Methylpropan-2-yl)oxy]-1,3-thiazole
• CAS: 69096-71-5
• 化学式: C₇H₁₁NOS
• 分子量: 157.236
• InChiKey: IAXKXAZFWVFEOV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  50.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-硝基噻唑 、 sodium t-butanolate 以 叔丁醇 为溶剂， 生成 2-butoxythiazole
  参考文献：
  名称：

  Forlani, Luciano, Journal of the Chemical Society. Perkin transactions II, 1991, # 11, p. 1699 - 1702

  摘要：

  DOI：

文献信息

• Novel Dosage Form
  申请人：NeuroVive Pharmaceutical AB

  公开号：US20140234414A1

  公开（公告）日：2014-08-21

  There is provided inter alia a pharmaceutical dosage form for oral administration comprising a sanglifehrin as active ingredient in which the sanglifehrin active ingredient is protected from acid degradation in the stomach environment following oral administration.

  提供了一种用于口服的药物剂型，包括桑格利非林作为活性成分，其中桑格利非林活性成分在口服后受到胃酸降解的保护。
• Endoparasitic depsipeptides
  申请人：Zoetis Services LLC

  公开号：US11331369B2

  公开（公告）日：2022-05-17

  The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.

  本发明提供了式 (1) 的环状去肽类化合物、其立体异构体及其兽药可接受盐类 其中R1、R2、R3、R4、L1和L2各自如本文所定义。本发明还考虑用式（1）化合物作为内吸杀虫剂的组合物和处理方法。
• 4-AZETIDINYL-1-HETEROARYL-CYCLOHEXANOL ANTAGONISTS OF CCR2
  申请人：Janssen Pharmaceutica NV

  公开号：EP2376475B1

  公开（公告）日：2015-09-02
• N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION
  申请人：C4 Therapeutics, Inc.

  公开号：US20200140456A1

  公开（公告）日：2020-05-07

  This invention provides Degronimers that have E3 Ubiquitin Ligase targeting moieties (Degrons) that can be linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation. The invention also provides Degrons that can be used to treat disorders mediated by cereblon or an Ikaros family protein, and methods of use and compositions thereof as well as methods for their preparation.
• Endoparasitic Depsipeptides
  申请人：Zoetis Services LLC

  公开号：US20200282016A1

  公开（公告）日：2020-09-10

  The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R 1 , R 2 , R 3 , R 4 , L 1 , and L 2 , are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.