2-Cyclopropylmethylene-malonaldehyde | 118348-06-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Cyclopropylmethylene-malonaldehyde
• 英文别名: 2-(Cyclopropylmethylidene)propanedial
• CAS: 118348-06-4
• 化学式: C₇H₈O₂
• 分子量: 124.139
• InChiKey: UCXLWCJWKNYZKB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  乙烯基乙醚 、 2-Cyclopropylmethylene-malonaldehyde 以 乙醚 为溶剂， 生成 4-Cyclopropyl-6-ethoxy-5,6-dihydro-4H-pyran-3-carbaldehyde
  参考文献：
  名称：

  Synthesis of (2,2-diformylethenyl)cycloalkanes and ?-?-bis-(2,2-diformylethenyl)alkanes

  摘要：

  The reaction of dimethylaminomethylenemalonaldehyde with Grignard reagents, which proceeds through 1,4-addition and is accompanied by the loss of the dimethylamino group, gives previously unreported (2,2-diformylethenyl)cycloalkanes and alpha,omega-bis-(2,2-diformylethenyl)alkanes, which were characterized as dihydropyran [4 + 2]-cycloadducts with vinyl ethyl ether.

  DOI：

  10.1007/bf00958284
• 作为产物：
  描述：

  dimethylaminomethylenemalonaldehyde 、 环丙基溴化镁 在 高氯酸 作用下， 生成 2-Cyclopropylmethylene-malonaldehyde
  参考文献：
  名称：

  Synthesis of (2,2-diformylethenyl)cycloalkanes and ?-?-bis-(2,2-diformylethenyl)alkanes

  摘要：

  The reaction of dimethylaminomethylenemalonaldehyde with Grignard reagents, which proceeds through 1,4-addition and is accompanied by the loss of the dimethylamino group, gives previously unreported (2,2-diformylethenyl)cycloalkanes and alpha,omega-bis-(2,2-diformylethenyl)alkanes, which were characterized as dihydropyran [4 + 2]-cycloadducts with vinyl ethyl ether.

  DOI：

  10.1007/bf00958284

文献信息

• ARNOLD, Z.;KRYSHTAL, G. V.;KRAL, V.;DVORAK, D.;YANOVSKAYA, L. A., TETRAHEDRON. LETT., 29,(1988) N 23, C. 2861-2864
  作者：ARNOLD, Z.、KRYSHTAL, G. V.、KRAL, V.、DVORAK, D.、YANOVSKAYA, L. A.

  DOI：——

  日期：——
• Synthesis of (2,2-diformylethenyl)cycloalkanes and ?-?-bis-(2,2-diformylethenyl)alkanes
  作者：G. V. Kryshtal'、V. Kral、D. Dvorzhak、Z. Arnold、L. A. Yanovskaya

  DOI：10.1007/bf00958284

  日期：1990.9

  The reaction of dimethylaminomethylenemalonaldehyde with Grignard reagents, which proceeds through 1,4-addition and is accompanied by the loss of the dimethylamino group, gives previously unreported (2,2-diformylethenyl)cycloalkanes and alpha,omega-bis-(2,2-diformylethenyl)alkanes, which were characterized as dihydropyran [4 + 2]-cycloadducts with vinyl ethyl ether.