5-Methyl-1,3,5-heptatrien | 58434-77-8

• 分子结构分类: 有机化合物 - 碳氢化合物 - 不饱和烃
• 英文名称: 5-Methyl-1,3,5-heptatrien
• 英文别名: (E,E)-1,3,5-Heptatriene, 5-methyl-；(3E,5E)-5-methylhepta-1,3,5-triene
• CAS: 58434-77-8
• 化学式: C₈H₁₂
• 分子量: 108.183
• InChiKey: HBOBXPNYRYGOCI-ZCOYIIAOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  (E)-5-methyl-1,5-heptadien-4-ol 在 potassium hydrogensulfate 作用下， 生成 5-Methyl-1,3,5-heptatrien
  参考文献：
  名称：

  Microbiological survey of dialysate: Vantage of use of sterile bag concentrate

  摘要：

  SummaryHaemodialysed patients are exposed to nearly 400 litres of dialysis water weekly. The bacterial contamination of treated dialysate and water induces acute pyrogenic reactions or chronic damage and cytokine activation.The aim of this study was to value the microbiological parameters of dialysis water and dialysate of our monitors by bacterial culture (measured as colony forming units [CFU]) of water samples at 37 °C after 48 hours, at 22 °C after 72 hours and after seven days, and by measuring endotoxin levels (endotoxin units [EU]).In our centre, there are 16 monitors (6 monitors use sterile dialysate fluid and 10 monitors use non sterile dialysate fluid). The chemicals used for disinfection are chlorine and paracetic acid. Water samples were taken under sterile procedures every three months for a year.No bacteria were found in the samples of water of the dialysis ring; EU were lower than the limit value of 0.25 EU/ml fixed by the European Pharmacopoeia.The concentration of CFU and EU of the dialysate, taken from monitors with a sterile bag, were lower than those of other monitors (p < 0.05 t Student test). However, the levels of CFU/ml and EU/ml of dialysate samples, taken from monitors with a non‐sterile bag, were lower than the guideline value of the European Pharmacopoeia (v.n. CFU < 50 CFU/ml and EU < 0,05 EU/ml).Frequent examination of CFU and EU is essential to reduce the damage caused by the use of contaminated water, therefore the goal of future dialytic techniques will be the use of “sterile dialysate”.

  DOI：

  10.1111/j.1755-6686.2001.tb00160.x

文献信息

• Ru(0)-Catalyzed Straightforward Synthesis of Conjugated Tetraenes: An Approach using Two Internal Alkynes with 1,3-Butadiene
  作者：Sayori Kiyota、Masafumi Hirano

  DOI：10.1021/acs.organomet.7b00801

  日期：2018.1.22

  The Ru(0)-catalyzed straightforward synthesis of conjugated tetraenes has been achieved in up to 85% yield by coupling of 2 equiv of internal alkynes with 1,3-butadiene at room temperature. The stoichiometric reaction of [Ru(η4-cisoid-1,3-butadiene)(η4-1,5-COD)(NCMe)] with 2 equiv of 3-hexyne produces a tetraene complex of Ru(0), [Ru3–6-η4-(3E,5E,7E,9E)-4,9-diethyldodeca-3,5,7,9-tetraene}(η4-1,5-COD)(NCMe)]

  通过在室温下将2个当量的内部炔烃与1,3-丁二烯偶联，可以以高达85％的产率实现Ru（0）催化的共轭四烯的直接合成。的化学计量反应的[Ru（η 4 - cisoid -1,3-丁二烯）（η 4 -1,5-二COD）（NCMe）]与2当量3-己炔的产生复杂的Ru（0）的四烯，[茹3-6-η 4 - （3- ê，5 ë，7 ê，9 ë）-4,9- diethyldodeca -3,5,7,9-四烯}（η 4 -1,5-二COD）（ NCMe）]，产率为98％，通过与1,3-丁二烯接触，以92％的产率释放出共轭四烯配体。
• Boccara,N.; Maitte,P., Bulletin de la Societe Chimique de France, 1972, p. 1463 - 1477
  作者：Boccara,N.、Maitte,P.

  DOI：——

  日期：——