3-[[(2R,3R,4S,5S,6S)-3,4,5-tris(3-hydroxypropoxy)-6-methoxyoxan-2-yl]methoxy]propan-1-ol | 1422512-84-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-[[(2R,3R,4S,5S,6S)-3,4,5-tris(3-hydroxypropoxy)-6-methoxyoxan-2-yl]methoxy]propan-1-ol
• CAS: 1422512-84-2
• 化学式: C₁₉H₃₈O₁₀
• 分子量: 426.505
• InChiKey: GCNUSOSMERSJBN-GFEQUFNTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.8
• 重原子数：
  29
• 可旋转键数：
  18
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  136
• 氢给体数：
  4
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  Methyl 2,3,4,6-tetra-O-allyl-α-D-mannopyranoside 在 9-硼双环[3.3.1]壬烷 作用下， 以 四氢呋喃 为溶剂， 生成 3-[[(2R,3R,4S,5S,6S)-3,4,5-tris(3-hydroxypropoxy)-6-methoxyoxan-2-yl]methoxy]propan-1-ol
  参考文献：
  名称：

  Chirally Homogeneous and Heterogeneous Dendritic Liquid Crystals

  摘要：

  We have coupled methyl alpha-D-glucoside (G) and methyl alpha-D-mannoside (M) as the chiral structural variant moieties in the core and at the branching sites within dendritic scaffolds surrounded by 12 cyanobiphenyl mesogens (CB). Systematic studies of the influence of the chiral moieties on thermal and mesomorphic properties were carried out by positional permutation approach of the pyranose units G and M within the core and branching points. The mesomorphic properties of the chirally homogeneous dendrimers GG(4)/MM4 and the corresponding chirally heterogeneous dendritic homologues GM(4)/MG(4) were investigated by differential scanning calorimetry (DSC) and polarized optical microscopy (POM). Remarkably, the thermal profile and the mesophase structure of the four dendrimers appear to be significantly independent of the nature of the central chiral core. The outer chirality at the periphery significantly dominates the liquid crystalline properties.

  DOI：

  10.1021/ma3026332

文献信息

• Chirally Homogeneous and Heterogeneous Dendritic Liquid Crystals
  作者：A. Belaissaoui、I. M. Saez、S. J. Cowling、J. W. Goodby

  DOI：10.1021/ma3026332

  日期：2013.2.26

  We have coupled methyl alpha-D-glucoside (G) and methyl alpha-D-mannoside (M) as the chiral structural variant moieties in the core and at the branching sites within dendritic scaffolds surrounded by 12 cyanobiphenyl mesogens (CB). Systematic studies of the influence of the chiral moieties on thermal and mesomorphic properties were carried out by positional permutation approach of the pyranose units G and M within the core and branching points. The mesomorphic properties of the chirally homogeneous dendrimers GG(4)/MM4 and the corresponding chirally heterogeneous dendritic homologues GM(4)/MG(4) were investigated by differential scanning calorimetry (DSC) and polarized optical microscopy (POM). Remarkably, the thermal profile and the mesophase structure of the four dendrimers appear to be significantly independent of the nature of the central chiral core. The outer chirality at the periphery significantly dominates the liquid crystalline properties.