(4-(1-(1-ethoxyethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate | 1269823-07-5

分子结构分类

有机化合物 - 有机杂环化合物 - 二嗪类

中文名称

——

中文别名

——

英文名称

(4-(1-(1-ethoxyethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate

英文别名

[4-[1-(1-ethoxyethyl)pyrazol-4-yl]pyrrolo[2,3-c]pyridazin-7-yl]methyl 2,2-dimethylpropanoate

(4-(1-(1-ethoxyethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate化学式

CAS

1269823-07-5

化学式

C₁₉H₂₅N₅O₃

mdl

——

分子量

371.439

InChiKey

IQFHAQGDTXRIRX-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

2.2
重原子数：

27
可旋转键数：

8
环数：

3.0
sp3杂化的碳原子比例：

0.47
拓扑面积：

84.1
氢给体数：

0
氢受体数：

6

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	(4-chloro-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-06-4	C₁₂H₁₄ClN₃O₂	267.715

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	(4-(1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-13-3	C₁₅H₁₇N₅O₂	299.332
——	(4-(1-(1-cyano-3-cyclopropylpropan-2-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-51-9	C₂₂H₂₆N₆O₂	406.487
——	(4-(1-(2-cyano-1-cyclopropylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-41-7	C₂₁H₂₄N₆O₂	392.461
——	(4-(1-(1-cyano-3-cyclohexylpropan-2-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-38-2	C₂₅H₃₂N₆O₂	448.568
——	(4-(1-(1-cyano-3-cyclopentylpropan-2-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-35-9	C₂₄H₃₀N₆O₂	434.541
——	(4-(1-(2-cyano-1-cyclobutylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-43-9	C₂₂H₂₆N₆O₂	406.487
——	(4-(1-(2-formylcyclopentyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-91-7	C₂₁H₂₅N₅O₃	395.461
——	(4-(1-(1-(cyanomethyl)cyclopentyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-29-1	C₂₂H₂₆N₆O₂	406.487
——	(4-(1-(2-cyano-1-cyclohexylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-24-6	C₂₄H₃₀N₆O₂	434.541
——	(4-(1-(2-cyanocyclopentyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-90-6	C₂₁H₂₄N₆O₂	392.461
——	(4-(1-(3-(cyanomethyl)oxetan-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-22-4	C₂₀H₂₂N₆O₃	394.433
——	(4-(1-(3-(cyanomethyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-32-6	C₂₀H₂₃N₇O₂	393.448
——	(R)-(4-(1-(1-cyclopentyl-3-(methylsulfonyloxy)propyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-68-8	C₂₄H₃₃N₅O₅S	503.623
——	(R)-(4-(1-(3-oxo-1-phenylpropyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-79-1	C₂₄H₂₅N₅O₃	431.494
——	(R)-(4-(1-(2-cyano-1-phenylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-78-0	C₂₄H₂₄N₆O₂	428.494
——	(4-(1-(2-((methylsulfonyloxy)methyl)cyclopentyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-94-0	C₂₂H₂₉N₅O₅S	475.569
——	(R)-(4-(1-(1-(3-hydroxyphenyl)-3-oxopropyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-82-6	C₂₄H₂₅N₅O₄	447.494
——	(R)-(4-(1-(2-cyano-1-(3-hydroxyphenyl)ethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-81-5	C₂₄H₂₄N₆O₃	444.493
——	(4-(1-(3-(cyanomethyl)-1-(ethylsulfonyl)azetidin-3-yl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate	1269823-31-5	C₂₂H₂₇N₇O₄S	485.567
——	tert-butyl 3-(cyanomethyl)-3-(4-(7-(pivaloyloxymethyl)-7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)azetidine-1-carboxylate	1269823-20-2	C₂₅H₃₁N₇O₄	493.566
——	2-(1-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)cyclobutyl)acetonitrile	1269823-44-0	C₁₅H₁₄N₆	278.316
——	3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-4-cyclopropylbutane nitrile	1269823-50-8	C₁₆H₁₆N₆	292.343
——	3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-cyclopropylpropane nitrile	1269823-40-6	C₁₅H₁₄N₆	278.316
——	(R)-3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropan-1-ol	1269823-65-5	C₁₇H₂₁N₅O	311.387
——	(R)-4-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-4-cyclopentylbutanenitrile	1269823-67-7	C₁₈H₂₀N₆	320.397
——	2-(1-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)cyclopentyl)acetonitrile	1269823-28-0	C₁₆H₁₆N₆	292.343
——	2-(3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)oxetan-3-yl)acetonitrile	1269823-21-3	C₁₄H₁₂N₆O	280.289
——	3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-cyclobutylpropane nitrile	1269823-42-8	C₁₆H₁₆N₆	292.343
——	2-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)cyclopentane carbonitrile	1269823-89-3	C₁₅H₁₄N₆	278.316
——	(S)-3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-4-cyclopentylbutanenitrile	1269823-56-4	C₁₈H₂₀N₆	320.397
——	3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-4-cyclopentylbutane nitrile	1269823-34-8	C₁₈H₂₀N₆	320.397
——	2-(1-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)cyclohexyl)acetonitrile	1269823-46-2	C₁₇H₁₈N₆	306.37
——	2-(2-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)cyclopentyl)acetonitrile	1269823-95-1	C₁₆H₁₆N₆	292.343
——	3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-4-cyclohexylbutane nitrile	1269823-37-1	C₁₉H₂₂N₆	334.424
——	(R)-3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentyl propanenitrile	1269823-11-1	C₁₇H₁₈N₆	306.37
——	(S)-3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentyl propanenitrile	1269823-16-6	C₁₇H₁₈N₆	306.37
——	(R)-3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-cyclohexylpropanenitrile	1269823-53-1	C₁₈H₂₀N₆	320.397
——	3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-cyclohexylpropane nitrile	1269823-23-5	C₁₈H₂₀N₆	320.397
——	(R)-3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-phenylpropane nitrile	1269823-77-9	C₁₈H₁₄N₆	314.349
——	(R)-3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-(3-hydroxyphenyl)propanenit