(E)-1,3-diphenyl-5-(4-methylphenyl)-4-yn-1-ene | 1297593-96-4

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: (E)-1,3-diphenyl-5-(4-methylphenyl)-4-yn-1-ene
• 英文别名: 1-[(E)-3,5-diphenylpent-1-en-4-ynyl]-4-methylbenzene
• CAS: 1297593-96-4
• 化学式: C₂₄H₂₀
• 分子量: 308.423
• InChiKey: SLDVRJXXBNZRIV-HTXNQAPBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  3-(4-methylphenyl)-1-phenylprop-2-en-1-ol 、 苯乙炔 在 copper(II) bis(trifluoromethanesulfonate) 作用下， 以 1,2-二溴乙烷 为溶剂， 反应 12.0h， 生成 (E)-1,5-diphenyl-3-(4-methylphenyl)-4-yn-1-ene 、 (E)-1,3-diphenyl-5-(4-methylphenyl)-4-yn-1-ene
  参考文献：
  名称：

  Cu(OTf)2-catalyzed arylmethylation of terminal alkynes with benzylic alcohols under ligand-, base-, and additive-free reaction conditions

  摘要：

  An effective, convenient, and mild coupling reaction of benzylic alcohols with terminal alkynes has been developed. As an effective Lewis acid, Cu(OTF)(2)-catalyzed arylmethylation of terminal alkynes with benzylic alcohols generated the corresponding products in BrCH2CH2Br with good yields in the absence of ligand, base, and additive. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.02.050

文献信息

• Cu(OTf)2-catalyzed arylmethylation of terminal alkynes with benzylic alcohols under ligand-, base-, and additive-free reaction conditions
  作者：Kai Ren、Pinhua Li、Lei Wang、Xiuli Zhang

  DOI：10.1016/j.tet.2011.02.050

  日期：2011.4

  An effective, convenient, and mild coupling reaction of benzylic alcohols with terminal alkynes has been developed. As an effective Lewis acid, Cu(OTF)(2)-catalyzed arylmethylation of terminal alkynes with benzylic alcohols generated the corresponding products in BrCH2CH2Br with good yields in the absence of ligand, base, and additive. (C) 2011 Elsevier Ltd. All rights reserved.