2-[2-(6-Ethenylpyridin-2-yl)oxyethoxy]ethanol | 943226-22-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-[2-(6-Ethenylpyridin-2-yl)oxyethoxy]ethanol
• 英文别名: 2-[2-(6-ethenylpyridin-2-yl)oxyethoxy]ethanol
• CAS: 943226-22-0
• 化学式: C₁₁H₁₅NO₃
• 分子量: 209.245
• InChiKey: JBAROHXTTZHRJN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  51.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-[2-(6-Ethenylpyridin-2-yl)oxyethoxy]ethanol 、 2,6-bis[(tosyloxy)methyl]pyridine 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 反应 25.0h， 以26%的产率得到2,6-Bis[2-[2-(6-ethenylpyridin-2-yl)oxyethoxy]ethoxymethyl]pyridine
  参考文献：
  名称：

  Synthesis of crownophanes possessing three pyridine rings

  摘要：

  Novel crownophanes with three pyridine moieties (pyridinocrownophanes 4 and 5) were prepared by means of intramolecular [2+2] photocycloaddition of vinylpyridine derivatives. In the liquid-liquid extraction of heavy metal cations, 4 and 5 exhibited high efficiency toward Ag+. Comparing the high extractability and complexing stability constant for Ag+ to those of the corresponding pyridinocrownophanes 2 and 3 and observing the H-1 NMR spectra in the presence of Ag+. the ethereal oxygen atoms and the three nitrogen atoms were found efficiently and cooperatively to act as ligating sites. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2007.03.099
• 作为产物：
  描述：

  2,6-二溴吡啶 在 四(三苯基膦)钯 2,6-二叔丁基-4-甲基苯酚 、 sodium hydride 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 反应 9.5h， 生成 2-[2-(6-Ethenylpyridin-2-yl)oxyethoxy]ethanol
  参考文献：
  名称：

  Synthesis of crownophanes possessing three pyridine rings

  摘要：

  Novel crownophanes with three pyridine moieties (pyridinocrownophanes 4 and 5) were prepared by means of intramolecular [2+2] photocycloaddition of vinylpyridine derivatives. In the liquid-liquid extraction of heavy metal cations, 4 and 5 exhibited high efficiency toward Ag+. Comparing the high extractability and complexing stability constant for Ag+ to those of the corresponding pyridinocrownophanes 2 and 3 and observing the H-1 NMR spectra in the presence of Ag+. the ethereal oxygen atoms and the three nitrogen atoms were found efficiently and cooperatively to act as ligating sites. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2007.03.099

文献信息

• Synthesis of crownophanes possessing three pyridine rings
  作者：Seiichi Inokuma、Takayaki Yatsuzuka、Shinji Ohtsuki、Shota Hino、Jun Nishimura

  DOI：10.1016/j.tet.2007.03.099

  日期：2007.6

  Novel crownophanes with three pyridine moieties (pyridinocrownophanes 4 and 5) were prepared by means of intramolecular [2+2] photocycloaddition of vinylpyridine derivatives. In the liquid-liquid extraction of heavy metal cations, 4 and 5 exhibited high efficiency toward Ag+. Comparing the high extractability and complexing stability constant for Ag+ to those of the corresponding pyridinocrownophanes 2 and 3 and observing the H-1 NMR spectra in the presence of Ag+. the ethereal oxygen atoms and the three nitrogen atoms were found efficiently and cooperatively to act as ligating sites. (c) 2007 Elsevier Ltd. All rights reserved.