8-羟基喹啉葡糖苷酸 | 14683-61-5

• 物质功能分类: 医药中间体 - 杂环化合物 - 喹啉类化合物
• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 8-羟基喹啉葡糖苷酸
• 中文别名: 8-喹啉基 BETA-D-吡喃葡糖苷酸
• 英文名称: 8-Hydroxyquinoline glucuronide
• 英文别名: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-quinolin-8-yloxyoxane-2-carboxylic acid
• CAS: 14683-61-5
• 化学式: C₁₅H₁₅NO₇
• mdl: MFCD00063949
• 分子量: 321.28
• InChiKey: DPEGQJDYRIQRHI-DKBOKBLXSA-N

物化性质

• 沸点：
  639.9±55.0 °C(Predicted)
• 密度：
  1.626±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  129
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• [EN] NOVEL INDICATOR PLATFORM<br/>[FR] NOUVELLE PLATEFORME INDICATRICE
  申请人：BIOSYNTH AG

  公开号：WO2010128120A1

  公开（公告）日：2010-11-11

  A novel indicator platform comprises a plurality of 1 H-lndol-3-yl indicator compounds that are capable of converting to a signalophore compound in response to an external stimulus. In one class of indicator compounds, the resulting signalophores are 2-benzylideneindoline compounds that are formed by an intermolecular Aldol-type process; in a further class of indicator compounds, the resulting signalophores are 10H-indolo[1,2-a]indole compounds that are formed by an intramolecular Aldol-type process. The indicators can be used in a wide array of applications relating, for example, to biological systems or optical data storage.

  一种新颖的指示剂平台包括多种1H-吲哚-3-基指示化合物，这些化合物能够在外部刺激作用下转化为信号体化合物。在一类指示化合物中，产生的信号体是通过分子间Aldol型过程形成的2-苄基亚甲基吲哚化合物；在另一类指示化合物中，产生的信号体是通过分子内Aldol型过程形成的10H-吲哚[1,2-a]吲哚化合物。这些指示剂可用于涉及生物系统或光学数据存储等各种应用中。
• 8-HYDROXY QUINOLINE DERIVATIVES
  申请人：PRANA BIOTECHNOLOGY LIMITED

  公开号：US20150094334A1

  公开（公告）日：2015-04-02

  The present invention describes a method for the treatment of a neurological condition in a subject which comprises administering to a subject in need thereof a therapeutically effect amount of a compound of the formula or pharmaceutically acceptable salts, hydrates, or solvates thereof.

  本发明描述了一种治疗受试者神经疾病的方法，包括向需要治疗的受试者施用公式中的化合物或其药学上可接受的盐、水合物或溶剂化物的治疗有效量。
• Agents and methods for spectrometric analysis
  申请人：Morpho Detection, Inc.

  公开号：EP2192408A1

  公开（公告）日：2010-06-02

  Disclosed herein are agents, methods, and kits for determining the presence or concentration of a target, or multiple targets, in a sample, in a uniplexed or multiplexed fashion. In general, the methods enable the analysis of small molecules produced or consumed in liquid-phase that may be analyzed using gas or vapor phase detection methods.

  本文公开了以单复用或多复用方式确定样品中目标或多个目标的存在或浓度的制剂、方法和试剂盒。一般来说，这些方法可以分析在液相中产生或消耗的小分子，这些小分子可以使用气相或气相检测方法进行分析。
• Novel indicator platform
  申请人：Biosynth AG

  公开号：EP2256103A1

  公开（公告）日：2010-12-01

  A novel indicator platform comprises a plurality of 1H-Indol-3-yl indicator compounds that are capable of converting to a signalophore compound in response to an external stimulus. In one class of indicator compounds, the resulting signalophores are 2-benzylideneindoline compounds that are formed by an intermolecular Aldol-type process; in a further class of indicator compounds, the resulting signalophores are 10H-indolo[1,2-a]indole compounds that are formed by an intramolecular Aldol-type process. The indicators can be used in a wide array of applications relating, for example, to biological systems or optical data storage.

  一种新型指示剂平台由多种 1H-吲哚-3-基指示剂化合物组成，这些化合物能够在外部刺激下转化为信号团化合物。在一类指示剂化合物中，产生的信号团是通过分子间醛醇型过程形成的 2-亚苄基吲哚啉化合物；在另一类指示剂化合物中，产生的信号团是通过分子内醛醇型过程形成的 10H-吲哚并[1,2-a]吲哚化合物。这些指示剂可广泛应用于生物系统或光学数据存储等领域。
• Test media and quantitative or qualitative method for identification and differentiation of biological materials in a test sample
  申请人：Micrology Laboratories L.L.C.

  公开号：EP2316964A1

  公开（公告）日：2011-05-04

  A test medium and method for detecting, quantifying, identifying and differentiating up to four (4) separate biological materials in a test sample. A test medium is disclosed which allows quantifying and differentiating under ambient light aggregates of biological entities producing specific enzymes, which might include general coliforms, E. coli, Aeromonas, and Salmonella in a single test medium. A new class of nonchromogenic substrates is disclosed which produce a substantially black, non-diffusible precipitate. This precipitate is not subject to interference from other chromogenic substrates present in the test medium.; In one embodiment, the substrates are selected such that E. coli colonies present in the test medium show as substantially black, general coliforms colonies show in the test medium as a blue-violet color, Aeromonas colonies present in the test medium show as a generally red-pink color, and Salmonella colonies show as a generally teal-green color. Other microorganisms and color possibilities for detection and quantification thereof are also disclosed. An inhibitor and method for making a test medium incorporating the inhibitor are disclosed.

  一种检测介质和方法，用于检测、量化、识别和区分检测样本中多达四（4）种不同的生物材料。本发明公开了一种测试介质，可在环境光下对产生特定酶的生物实体聚集体进行定量和区分，这些生物实体可能包括单个测试介质中的普通大肠菌群、大肠杆菌、气单胞菌和沙门氏菌。公开了一类新的非变色基质，这种基质会产生一种黑色的、不可扩散的沉淀物。在一个实施方案中，基质的选择是这样的：存在于测试培养基中的大肠杆菌菌落显示为黑色，一般大肠菌群菌落显示为蓝紫色，存在于测试培养基中的气单胞菌菌落显示为粉红色，沙门氏菌菌落显示为茶绿色。此外，还公开了其他微生物及其检测和定量的颜色可能性。此外，还公开了一种抑制剂和制作含有该抑制剂的测试培养基的方法。