1,3-Dioxolane, 2-isopentyl-2-methyl- | 14447-30-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,3-Dioxolane, 2-isopentyl-2-methyl-
• 英文别名: 2-methyl-2-(3-methylbutyl)-1,3-dioxolane
• CAS: 14447-30-4
• 化学式: C₉H₁₈O₂
• 分子量: 158.24
• InChiKey: PUKFTKNHQBDBPV-UHFFFAOYSA-N

物化性质

• 沸点：
  168.3±8.0 °C(Predicted)
• 密度：
  0.895±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,3-Dioxolane, 2-isopentyl-2-methyl- 、 水 、 草酸 以92%的产率得到
  参考文献：
  名称：

  JULIA M.; BADET B., BULL. SOC. CHIM. FRANCE , 1975, NO 5-6, PART. 2, 1363-1366, 21

  摘要：

  DOI：
• 作为产物：
  描述：

  2-[2-(benzenesulfonyl)-3-methylbutyl]-2-methyl-1,3-dioxolane 、 甲醇 以91%的产率得到
  参考文献：
  名称：

  JULIA M.; BADET B., BULL. SOC. CHIM. FRANCE , 1975, NO 5-6, PART. 2, 1363-1366, 21

  摘要：

  DOI：

文献信息

• NOVEL INDOLE DERIVATIVES AND THEIR USE IN NEURODEGENERATIVE DISEASES
  申请人：Merck Patent GmbH

  公开号：US20160168090A1

  公开（公告）日：2016-06-16

  The present invention relates to indole compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of P2X7, and for the treatment of P2X7-related disorders.

  本发明涉及吲哚化合物及其药用可接受的组合物，用作P2X7拮抗剂，用于治疗与P2X7相关的疾病。
• Macrocyclic inhibitors of flaviviridae viruses
  申请人：Cypralis Limited

  公开号：US10472392B2

  公开（公告）日：2019-11-12

  Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.

  本文提供了式 I 的化合物及其药学上可接受的盐类和酯类。 所提供的化合物、组合物和方法可用于治疗病毒感染，尤其是丙型肝炎感染。
• ANTIGEN-PRESENTING SCAFFOLDS
  申请人：Burn Paul Leslie

  公开号：US20110274713A1

  公开（公告）日：2011-11-10

  The invention relates to compounds having formula (I): Scaffold-[L-(Antigen) t ] y (I) wherein Antigen represents at least a portion of a target antigen for modulating an immune response; wherein t is 0 or an integer of at least 1; wherein y is at least 1; wherein the number of Antigens on the Scaffold is at least 2; wherein L is a linking group or a covalent bond, wherein when L is a covalent bond, the covalent bond is a single bond attached to a sp or sp 2 hybridized atom of the Scaffold and when L is a linking group, the linking group is attached to the Scaffold through a single bond attached to a sp or sp 2 hybridized atom; whereby the Scaffold is sufficiently rigid to maintain the relative position of the single bonds attached to sp or sp 2 hybridized atoms. Further described are compositions containing the compounds and methods of using them.
• MACROCYCLIC INHIBITORS OF FLAVIVIRIDAE VIRUSES
  申请人：Selcia Limited

  公开号：US20170190734A1

  公开（公告）日：2017-07-06

  Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.
• JULIA M.; BADET B., BULL. SOC. CHIM. FRANCE <BSCF-AS>, 1975, NO 5-6, PART. 2, 1363-1366, 21
  作者：JULIA M.、 BADET B.

  DOI：——

  日期：——