(S)-(+)-2,2-dimethyl-4-tetradecyl-1,3-dioxolane | 172477-10-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (S)-(+)-2,2-dimethyl-4-tetradecyl-1,3-dioxolane
• 英文别名: (4S)-2,2-dimethyl-4-tetradecyl-1,3-dioxolane
• CAS: 172477-10-0
• 化学式: C₁₉H₃₈O₂
• 分子量: 298.51
• InChiKey: BCDDJRMKBGAVTF-SFHVURJKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.7
• 重原子数：
  21
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (S)-(+)-2,2-dimethyl-4-tetradecyl-1,3-dioxolane 在 盐酸 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以91%的产率得到1,2-十六烷二醇
  参考文献：
  名称：

  Synthesis and configurational assignment of (R) and (S)-2-bromohexadecanoic acids

  摘要：

  Synthesis of bath enantiomers of 2-bromohexadecanoic acid is described by diastereoselective bromination of esters (+)- and (-)-3 followed by removal of the chiral auxiliary. The absolute configuration of the acids is confirmed by an independent chemical synthesis from chiral pool precursors.

  DOI：

  10.1016/0957-4166(95)00305-9
• 作为产物：
  描述：

  (S)-2,2-Dimethyl-4-((E)-tetradec-1-enyl)-[1,3]dioxolane 在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 以95%的产率得到(S)-(+)-2,2-dimethyl-4-tetradecyl-1,3-dioxolane
  参考文献：
  名称：

  Synthesis and configurational assignment of (R) and (S)-2-bromohexadecanoic acids

  摘要：

  Synthesis of bath enantiomers of 2-bromohexadecanoic acid is described by diastereoselective bromination of esters (+)- and (-)-3 followed by removal of the chiral auxiliary. The absolute configuration of the acids is confirmed by an independent chemical synthesis from chiral pool precursors.

  DOI：

  10.1016/0957-4166(95)00305-9

文献信息

• Synthesis and configurational assignment of (R) and (S)-2-bromohexadecanoic acids
  作者：David Hernanz、Francisco Camps、Angel Guerrero、Antonio Delgado

  DOI：10.1016/0957-4166(95)00305-9

  日期：1995.9

  Synthesis of bath enantiomers of 2-bromohexadecanoic acid is described by diastereoselective bromination of esters (+)- and (-)-3 followed by removal of the chiral auxiliary. The absolute configuration of the acids is confirmed by an independent chemical synthesis from chiral pool precursors.