(S)-4,7-dimethyl-6-octen-3-one | 1586020-54-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (S)-4,7-dimethyl-6-octen-3-one
• 英文别名: (4S)-4,7-dimethyloct-6-en-3-one
• CAS: 1586020-54-3
• 化学式: C₁₀H₁₈O
• 分子量: 154.252
• InChiKey: WKQWDIFHKYWRTA-VIFPVBQESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (3-甲基丁-2-烯基)丙二酸二乙酯 在 吡啶 、 lithium aluminium tetrahydride 、 Amano PS Lipase 、 戴斯-马丁氧化剂 、 magnesium 作用下， 以 四氢呋喃 、 1,4-二氧六环 、 乙醚 、 二氯甲烷 为溶剂， 反应 15.0h， 生成 (S)-4,7-dimethyl-6-octen-3-one
  参考文献：
  名称：

  Syntheses and odor properties of optically active dimethyl octenone and its analogs

  摘要：

  The optically active isomers of dimethyl octenone, which is used in citrus accords, and its analogs, were synthesized from a common chiral intermediate prepared by the lipase-catalyzed desymmetrization of prochiral diol. The results of an olfactory evaluation of the prepared isomers are also reported. (C) 2016 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2016.02.002

文献信息

• Investigation of a novel diamine based chiral auxiliary in the asymmetric alkylation of ketones
  作者：Sarah L. Clarke、Christina M. McSweeney、Gerard P. McGlacken

  DOI：10.1016/j.tetasy.2014.01.006

  日期：2014.2
• Syntheses and odor properties of optically active dimethyl octenone and its analogs
  作者：Masashi Kawasaki、Momo Shimizu、Saki Kuroyanagi、Yoshiaki Shishido、Tsuyoshi Komiyama、Naoki Toyooka

  DOI：10.1016/j.tetasy.2016.02.002

  日期：2016.4

  The optically active isomers of dimethyl octenone, which is used in citrus accords, and its analogs, were synthesized from a common chiral intermediate prepared by the lipase-catalyzed desymmetrization of prochiral diol. The results of an olfactory evaluation of the prepared isomers are also reported. (C) 2016 Elsevier Ltd. All rights reserved.