5-chloro-3-[[(5-chloro-3-formyl-2-hydroxyphenyl)methyl-[(1S)-1-phenylethyl]amino]methyl]-2-hydroxybenzaldehyde | 1620413-51-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-chloro-3-[[(5-chloro-3-formyl-2-hydroxyphenyl)methyl-[(1S)-1-phenylethyl]amino]methyl]-2-hydroxybenzaldehyde
• CAS: 1620413-51-5
• 化学式: C₂₄H₂₁Cl₂NO₄
• 分子量: 458.341
• InChiKey: UFANTOBFJYWLKE-HNNXBMFYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  31
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  77.8
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  lead(II) nitrate 、 5-chloro-3-[[(5-chloro-3-formyl-2-hydroxyphenyl)methyl-[(1S)-1-phenylethyl]amino]methyl]-2-hydroxybenzaldehyde 、 1,3-丙二胺 以 乙醇 为溶剂， 反应 2.17h， 以83%的产率得到
  参考文献：
  名称：

  Base-Induced Self-Assembly for One-Dimensional Coordination Polymers via Chiral Pendant-Armed Schiff Base Mononuclear Pb(II) Macrocycles

  摘要：

  A pair of 18-membered [1 + 1] chiral pendant-armed Schiff base macrocyclic mononuclear Pb(II) complexes with an unusual N1O2 coordination mode, synthesized from two chiral isomeric dialdehyde components, can be further self-assembled to one-dimensional ribbon coordination polymers by adding NaOH as a base to remove two phenolic protons.

  DOI：

  10.1021/ic5008846
• 作为产物：
  描述：

  (S)-(-)- α-甲基苄胺 、 5-chloro-3-(chloromethyl)-2-hydroxybenzaldehyde 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 9.0h， 以24%的产率得到5-chloro-3-[[(5-chloro-3-formyl-2-hydroxyphenyl)methyl-[(1S)-1-phenylethyl]amino]methyl]-2-hydroxybenzaldehyde
  参考文献：
  名称：

  Base-Induced Self-Assembly for One-Dimensional Coordination Polymers via Chiral Pendant-Armed Schiff Base Mononuclear Pb(II) Macrocycles

  摘要：

  A pair of 18-membered [1 + 1] chiral pendant-armed Schiff base macrocyclic mononuclear Pb(II) complexes with an unusual N1O2 coordination mode, synthesized from two chiral isomeric dialdehyde components, can be further self-assembled to one-dimensional ribbon coordination polymers by adding NaOH as a base to remove two phenolic protons.

  DOI：

  10.1021/ic5008846

文献信息

• Base-Induced Self-Assembly for One-Dimensional Coordination Polymers via Chiral Pendant-Armed Schiff Base Mononuclear Pb(II) Macrocycles
  作者：Kun Zhang、Chao Jin、Yuchen Sun、Feifan Chang、Wei Huang

  DOI：10.1021/ic5008846

  日期：2014.8.4

  A pair of 18-membered [1 + 1] chiral pendant-armed Schiff base macrocyclic mononuclear Pb(II) complexes with an unusual N1O2 coordination mode, synthesized from two chiral isomeric dialdehyde components, can be further self-assembled to one-dimensional ribbon coordination polymers by adding NaOH as a base to remove two phenolic protons.