(E)-3-phenyl-1-[4-[[3-[[4-[(E)-3-phenylprop-2-enoyl]phenoxy]methyl]-5-prop-2-ynoxyphenyl]methoxy]phenyl]prop-2-en-1-one | 1196532-73-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: (E)-3-phenyl-1-[4-[[3-[[4-[(E)-3-phenylprop-2-enoyl]phenoxy]methyl]-5-prop-2-ynoxyphenyl]methoxy]phenyl]prop-2-en-1-one
• CAS: 1196532-73-6
• 化学式: C₄₁H₃₂O₅
• 分子量: 604.702
• InChiKey: VGNFVUQKJCCIQR-RNIAWFEPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.5
• 重原子数：
  46
• 可旋转键数：
  14
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  61.8
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  (E)-3-phenyl-1-[4-[[3-[[4-[(E)-3-phenylprop-2-enoyl]phenoxy]methyl]-5-prop-2-ynoxyphenyl]methoxy]phenyl]prop-2-en-1-one 、 1,3-diazido-2,2-bis(azidomethyl)propane 在 copper(ll) sulfate pentahydrate 、 (+)-sodium-L-ascorbate 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 12.0h， 以59%的产率得到(E)-1-[4-[[3-[[1-[3-[4-[[3,5-bis[[4-[(E)-3-phenylprop-2-enoyl]phenoxy]methyl]phenoxy]methyl]triazol-1-yl]-2,2-bis[[4-[[3,5-bis[[4-[(E)-3-phenylprop-2-enoyl]phenoxy]methyl]phenoxy]methyl]triazol-1-yl]methyl]propyl]triazol-4-yl]methoxy]-5-[[4-[(E)-3-phenylprop-2-enoyl]phenoxy]methyl]phenyl]methoxy]phenyl]-3-phenylprop-2-en-1-one
  参考文献：
  名称：

  Synthesis and Characterization of Some Novel Dendritic Architectures Bearing Chalcone at the Periphery Through Click Approach

  摘要：

  Synthesis of 1,2,3-triazole-based dendritic architectures bearing a chalcone unit at the surface group has been achieved through a click reaction by the convergent synthetic strategy, in which tri- and tetra-azide were used as core units.

  DOI：

  10.1080/00397910902840827
• 作为产物：
  描述：

  (E)-1-[4-[[3-hydroxy-5-[[4-[(E)-3-phenylprop-2-enoyl]phenoxy]methyl]phenyl]methoxy]phenyl]-3-phenylprop-2-en-1-one 、 3-溴丙炔 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以84%的产率得到(E)-3-phenyl-1-[4-[[3-[[4-[(E)-3-phenylprop-2-enoyl]phenoxy]methyl]-5-prop-2-ynoxyphenyl]methoxy]phenyl]prop-2-en-1-one
  参考文献：
  名称：

  Synthesis and Characterization of Some Novel Dendritic Architectures Bearing Chalcone at the Periphery Through Click Approach

  摘要：

  Synthesis of 1,2,3-triazole-based dendritic architectures bearing a chalcone unit at the surface group has been achieved through a click reaction by the convergent synthetic strategy, in which tri- and tetra-azide were used as core units.

  DOI：

  10.1080/00397910902840827

文献信息

• Synthesis and Characterization of Some Novel Dendritic Architectures Bearing Chalcone at the Periphery Through Click Approach
  作者：Perumal Rajakumar、Sebastian Raja

  DOI：10.1080/00397910902840827

  日期：2009.10.12

  Synthesis of 1,2,3-triazole-based dendritic architectures bearing a chalcone unit at the surface group has been achieved through a click reaction by the convergent synthetic strategy, in which tri- and tetra-azide were used as core units.