1-(pyridin-3-yl)pentane-1,2-dione | 1587661-07-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(pyridin-3-yl)pentane-1,2-dione
• 英文别名: 1-Pyridin-3-ylpentane-1,2-dione；1-pyridin-3-ylpentane-1,2-dione
• CAS: 1587661-07-1
• 化学式: C₁₀H₁₁NO₂
• 分子量: 177.203
• InChiKey: MQJRUAROOHGMCT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  47
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-(pent-1-yn-1-yl)pyridine 在 mercuric(II) nitrate monohydrate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 0.33h， 以49%的产率得到1-(pyridin-3-yl)pentane-1,2-dione
  参考文献：
  名称：

  Synthesis of α-Diketones from Alkylaryl- and Diarylalkynes Using Mercuric Salts

  摘要：

  Both alkylarylalkynes and diarylalkynes 1 are converted into the alpha-diketones 2 in good yield by the use of mercuric salts, e.g., mercuric nitrate hydrate or mercuric triflate, in the presence of water. Other mercuric salts, e.g., sulfate, chloride, acetate, or trifluoroacetate, do not provide the diketone product. A possible mechanism is proposed.

  DOI：

  10.1021/ol500592m

文献信息

• Synthesis of α-Diketones from Alkylaryl- and Diarylalkynes Using Mercuric Salts
  作者：Michael E. Jung、Gang Deng

  DOI：10.1021/ol500592m

  日期：2014.4.18

  Both alkylarylalkynes and diarylalkynes 1 are converted into the alpha-diketones 2 in good yield by the use of mercuric salts, e.g., mercuric nitrate hydrate or mercuric triflate, in the presence of water. Other mercuric salts, e.g., sulfate, chloride, acetate, or trifluoroacetate, do not provide the diketone product. A possible mechanism is proposed.