7,8-dimethoxy-4-hydroxyquinolin-2(1H)-one | 43215-49-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 7,8-dimethoxy-4-hydroxyquinolin-2(1H)-one
• 英文别名: 4-hydroxy-7,8-dimethoxy-1H-quinolin-2-one；4-hydroxy-7,8-dimethoxy-1H-quinolin-2-one
• CAS: 43215-49-2
• 化学式: C₁₁H₁₁NO₄
• 分子量: 221.213
• InChiKey: BCTRHMVIMWNWNM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  67.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  7,8-dimethoxy-4-hydroxyquinolin-2(1H)-one 在 碘 、 sodium carbonate 作用下， 以 1,4-二氧六环 、 水 为溶剂， 反应 2.0h， 以66%的产率得到4-hydroxy-3-iodo-7,8-dimethoxyquinolin-2(1H)-one
  参考文献：
  名称：

  Synthesis of (+)-Myrtopsine, (+)-7,8-Dimethoxymyrtopsine, and Related 2,3-Dihydro-3-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran Natural Products

  摘要：

  DOI：

  10.3987/com-06-s(w)20
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 盐酸 作用下， 生成 7,8-dimethoxy-4-hydroxyquinolin-2(1H)-one
  参考文献：
  名称：

  Mookerjee; Bose, Journal of the Indian Chemical Society, 1946, vol. 23, p. 1,5

  摘要：

  DOI：

文献信息

• Watters, William H.; Ramachandran, Venkataraman N., Journal of Chemical Research, Miniprint, 1997, # 6, p. 1201 - 1215
  作者：Watters, William H.、Ramachandran, Venkataraman N.

  DOI：——

  日期：——
• Asahina; Nakanishi, Chemische Berichte, 1930, vol. 63, p. 2057
  作者：Asahina、Nakanishi

  DOI：——

  日期：——
• Tagawa, Yoshinobu; Kawaoka, Takamitsu; Goto, Yoshinobu, Journal of Heterocyclic Chemistry, 1997, vol. 34, # 6, p. 1677 - 1683
  作者：Tagawa, Yoshinobu、Kawaoka, Takamitsu、Goto, Yoshinobu

  DOI：——

  日期：——
• Self-consistent elastoplastic stress solutions for functionally graded material systems subjected to thermal transients
  作者：S. Pitakthapanaphong、E.P. Busso

  DOI：10.1016/s0022-5096(01)00105-3

  日期：2002.4

  In this work, a self-consistent constitutive framework is proposed to describe the behaviour of a generic three-layered system containing a functionally graded material (FGM) layer subjected to thermal loading. Analytical and semi-analytical solutions are obtained to describe the thermo-elastic and thermo-elastoplastic behaviour of a three-layered system consisting of a metallic and a ceramic layer joined together by an FGM layer of arbitrary composition profile. Solutions for the stress distributions in a generic FGM system subjected to arbitrary temperature transient conditions are presented. The homogenisation of the local elastoplastic FGM behaviour in terms of the properties of its individual phases is performed using a self-consistent approach. In this work, power-law strain hardening behaviour is assumed for the FGM metallic phase. The stress distributions within the FGM systems are compared with accurate numerical solutions obtained from finite element analyses and good agreement is found throughout. Solutions are also given for the critical temperature transients required for the onset of plastic deformation within the three-layered systems. (C) 2002 Elsevier Science Ltd. All rights reserved.
• Alkoxyl Interchange by γ-Alkoxyquinoline Derivatives in Alcoholic Alkali
  作者：B. Berinzaghi、V. Deulofeu、R. Labriola、A. Muruzabal

  DOI：10.1021/ja01247a027

  日期：1943.7