6'-chloro-6-nitro-4,4'-diphenyl-2,3'-biquinolin-2'(1'H)-one | 304446-46-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 6'-chloro-6-nitro-4,4'-diphenyl-2,3'-biquinolin-2'(1'H)-one
• 英文别名: 6-chloro-3-(6-nitro-4-phenylquinolin-2-yl)-4-phenyl-1H-quinolin-2-one
• CAS: 304446-46-6
• 化学式: C₃₀H₁₈ClN₃O₃
• 分子量: 503.944
• InChiKey: IFAVJCDYTHMOGN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  37
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  87.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1-(6-氯-2-羟基-4-苯基-喹啉-3-基)-乙酮 、 2-氨基-5-硝基二苯甲酮 在 硫酸 作用下， 以 溶剂黄146 为溶剂， 以88%的产率得到6'-chloro-6-nitro-4,4'-diphenyl-2,3'-biquinolin-2'(1'H)-one
  参考文献：
  名称：

  A Convenient Method of Facilitating Aryl–Aryl Bond-Formation Reactions in the Synthesis of Biquinoline- and Quinoline-Bearing Chromene Derivatives

  摘要：

  A method to derive functionalized biquinoline- and quinoline-bearing chromene bicyclic systems through aryl-aryl bond formation in a one-pot synthesis is described. The X-ray structure analysis provides insight into the mode of orientation of the molecules and opens the way to the synthesis of various hybrid molecules by making use of suitable substituents at R-1, R-2, and R-3.

  DOI：

  10.1055/s-0032-1317488

文献信息

• A Convenient Method of Facilitating Aryl–Aryl Bond-Formation Reactions in the Synthesis of Biquinoline- and Quinoline-Bearing Chromene Derivatives
  作者：Palathurai Mohan、Mathan Sankaran、Kumarasamy Chandraprakash、Chokkalingam Uvarani、Kailasam Vennila、Devadasan Velmurugan

  DOI：10.1055/s-0032-1317488

  日期：——

  A method to derive functionalized biquinoline- and quinoline-bearing chromene bicyclic systems through aryl-aryl bond formation in a one-pot synthesis is described. The X-ray structure analysis provides insight into the mode of orientation of the molecules and opens the way to the synthesis of various hybrid molecules by making use of suitable substituents at R-1, R-2, and R-3.