7,11-bis(2-furanyl)-[1,3]dioxolo[4,5-j]phenanthridine | 1433373-15-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 7,11-bis(2-furanyl)-[1,3]dioxolo[4,5-j]phenanthridine
• 英文别名: 7,11-Bis(furan-2-yl)-[1,3]dioxolo[4,5-j]phenanthridine；7,11-bis(furan-2-yl)-[1,3]dioxolo[4,5-j]phenanthridine
• CAS: 1433373-15-9
• 化学式: C₂₂H₁₃NO₄
• 分子量: 355.35
• InChiKey: LOUNYUZEFHXVMS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  27
• 可旋转键数：
  2
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  57.6
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2-呋喃硼酸 、 7,11-diiodo-[1,3]dioxolo[4,5-j]phenanthridine 在 四(三苯基膦)钯 、 potassium carbonate 作用下， 以 乙二醇二甲醚 、 水 为溶剂， 反应 0.33h， 以20%的产率得到7,11-bis(2-furanyl)-[1,3]dioxolo[4,5-j]phenanthridine
  参考文献：
  名称：

  Fluorescence sensing of Cu(II) based on trisphaeridine derivatives

  摘要：

  The design, synthesis, and ion-sensing properties of new 7,11-diaryltrisphaeridines are described. 2-Thiophenyl and 2-furanyl derivatives behave as highly selective fluorescence chemosensors for Cu2+ cations, with limits of detection (LOD) of 3.8 and 12.9 mu M, respectively, i.e. below the toxic level of Cu2+ (ca. 20 mu M); while the presence of 2-methoxyphenyl groups favors the selective detection of Cu2+ and lowers the LOD to 1.1 mu M. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.04.009

文献信息

• Fluorescence sensing of Cu(II) based on trisphaeridine derivatives
  作者：Alegría Caballero、Pedro J. Campos、Miguel A. Rodríguez

  DOI：10.1016/j.tet.2013.04.009

  日期：2013.6

  The design, synthesis, and ion-sensing properties of new 7,11-diaryltrisphaeridines are described. 2-Thiophenyl and 2-furanyl derivatives behave as highly selective fluorescence chemosensors for Cu2+ cations, with limits of detection (LOD) of 3.8 and 12.9 mu M, respectively, i.e. below the toxic level of Cu2+ (ca. 20 mu M); while the presence of 2-methoxyphenyl groups favors the selective detection of Cu2+ and lowers the LOD to 1.1 mu M. (C) 2013 Elsevier Ltd. All rights reserved.