1,1,3-trimethoxy-propene | 50284-74-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,1,3-trimethoxy-propene
• 英文别名: methoxymethyl-ketene dimethyl acetal；1,1,3-Trimethoxyprop-1-ene
• CAS: 50284-74-7
• 化学式: C₆H₁₂O₃
• 分子量: 132.159
• InChiKey: VBKUCGKXGUHMAD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1,1,3-trimethoxy-propene 、 (4-甲氧基-苯甲酰氨基)-乙酸 在 乙酸酐 作用下， 生成 2-(p-Anisyl)-4-(3'-methoxyallyliden)-oxazolon-(5)
  参考文献：
  名称：

  Jena,E.; Tripathy,P.B., Journal of the Indian Chemical Society, 1970, vol. 47, p. 251 - 254

  摘要：

  DOI：

文献信息

• NUCLEIC ACID BINDING DYES AND USES THEREFOR
  申请人：McDougall Mark

  公开号：US20100233710A1

  公开（公告）日：2010-09-16

  The invention provides novel compounds and compositions of Formulas I and II, as well as methods of using them. The compounds can be used, for example, to quantify an amount of double stranded DNA in a sample subjected to nucleic acid amplification, or for real time monitoring of a nucleic acid amplification reaction. The compounds can be provided in a kit, for example, with other reagents and instructions for using the compounds and reagents.

  这项发明提供了Formula I和Formula II的新化合物和组合物，以及使用它们的方法。这些化合物可以用于例如，在经过核酸扩增的样本中定量双链DNA的数量，或者用于实时监测核酸扩增反应。这些化合物可以作为一种试剂盒的一部分提供，例如，与其他试剂和使用这些化合物和试剂的说明书一起。
• Aza-benzazolium containing cyanine dyes
  申请人：——

  公开号：US20040137475A1

  公开（公告）日：2004-07-15

  Unsymmetrical cyanine dyes that incorporate an aza-benzazolium ring moiety are described, including cyanine dyes substituted by a cationic side chain, monomeric and dimeric cyanine dyes, chemically reactive cyanine dyes, and conjugates of cyanine dyes. The subject dyes are virtually non-fluorescent when diluted in aqueous solution, but exhibit bright fluorescence when associated with nucleic acid polymers such as DNA or RNA, or when associated with detergent-complexed proteins. A variety of applications are described for detection and quantitation of nucleic acids and detergent-complexed proteins in a variety of samples, including solutions, electrophoretic gels, cells, and microorganisms.

  描述了一种包含氮杂苯并咪唑环基团的不对称靛烷染料，包括带有阳离子侧链的靛烷染料，单体和二聚靛烷染料，化学反应性靛烷染料以及靛烷染料的共轭物。这些染料在水溶液中稀释时几乎不发荧光，但与核酸聚合物（如DNA或RNA）或与复合物化的蛋白质相结合时，会表现出明亮的荧光。描述了用于检测和定量各种样品中的核酸和复合物化蛋白质的各种应用，包括溶液、电泳凝胶、细胞和微生物。
• Aza-Benzazolium Containing Cyanine Dyes
  申请人：Haugland P. Richard

  公开号：US20080044811A1

  公开（公告）日：2008-02-21

  Unsymmetrical cyanine dyes that incorporate an aza-benzazolium ring moiety are described, including cyanine dyes substituted by a cationic side chain, monomeric and dimeric cyanine dyes, chemically reactive cyanine dyes, and conjugates of cyanine dyes. The subject dyes are virtually non-fluorescent when diluted in aqueous solution, but exhibit bright fluorescence when associated with nucleic acid polymers such as DNA or RNA, or when associated with detergent-complexed proteins. A variety of applications are described for detection and quantitation of nucleic acids and detergent-complexed proteins in a variety of samples, including solutions, electrophoretic gels, cells, and microorganisms.

  本文描述了包含氮杂苯并咪唑环基团的非对称青光菁染料，包括带有阳离子侧链的青光菁染料、单体和二聚体青光菁染料、化学反应性青光菁染料和青光菁染料的共轭物。当在水溶液中稀释时，这些染料几乎不发荧光，但当与核酸聚合物如DNA或RNA结合或与复合物化的蛋白质结合时，表现出明亮的荧光。本文还描述了在各种样品中检测和定量核酸和复合物化蛋白质的各种应用，包括溶液、电泳凝胶、细胞和微生物。
• AZA-BENZAZOLIUM CONTAINING CYANINE DYES
  申请人：HAUGLAND Richard P.

  公开号：US20110217696A1

  公开（公告）日：2011-09-08

  Unsymmetrical cyanine dyes that incorporate an aza-benzazolium ring moiety are described, including cyanine dyes substituted by a cationic side chain, monomeric and dimeric cyanine dyes, chemically reactive cyanine dyes, and conjugates of cyanine dyes. The subject dyes are virtually non-fluorescent when diluted in aqueous solution, but exhibit bright fluorescence when associated with nucleic acid polymers such as DNA or RNA, or when associated with detergent-complexed proteins. A variety of applications are described for detection and quantitation of nucleic acids and detergent-complexed proteins in a variety of samples, including solutions, electrophoretic gels, cells, and microorganisms.

  本文描述了包含氮杂苯并咪唑环基团的非对称青光菁染料，包括带有阳离子侧链的青光菁染料、单体和二聚体青光菁染料、化学反应性青光菁染料以及青光菁染料的共轭物。当在水溶液中稀释时，这些染料几乎不发荧光，但当与核酸聚合物（如DNA或RNA）或与洗涤剂复合的蛋白质结合时，会展现出明亮的荧光。本文描述了在各种样品中检测和定量核酸和洗涤剂复合蛋白质的各种应用，包括溶液、电泳凝胶、细胞和微生物。
• Aza-benzazolium Containing Cyanine Dyes
  申请人：Haugland Richard P.

  公开号：US20120295817A1

  公开（公告）日：2012-11-22

  Unsymmetrical cyanine dyes that incorporate an aza-benzazolium ring moiety are described, including cyanine dyes substituted by a cationic side chain, monomeric and dimeric cyanine dyes, chemically reactive cyanine dyes, and conjugates of cyanine dyes. The subject dyes are virtually non-fluorescent when diluted in aqueous solution, but exhibit bright fluorescence when associated with nucleic acid polymers such as DNA or RNA, or when associated with detergent-complexed proteins. A variety of applications are described for detection and quantitation of nucleic acids and detergent-complexed proteins in a variety of samples, including solutions, electrophoretic gels, cells, and microorganisms.

  本文介绍了包含氮杂苯并咪唑环基团的非对称青烷染料，包括带有阳离子侧链的青烷染料、单体和二聚体青烷染料、化学反应性青烷染料以及青烷染料的共轭物。这些染料在水溶液中稀释后几乎不发荧光，但与核酸聚合物如DNA或RNA或与复合物化蛋白质结合时会产生明亮的荧光。本文描述了在各种样品中检测和定量核酸和复合物化蛋白质的各种应用，包括溶液、电泳凝胶、细胞和微生物。