2-Allyloxymethyl-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadecane | 849905-41-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 2-Allyloxymethyl-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadecane
• 英文别名: 2-((Allyloxy)methyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane；2-(prop-2-enoxymethyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane
• CAS: 849905-41-5
• 化学式: C₁₆H₃₂N₂O₅
• 分子量: 332.44
• InChiKey: YZDRBNPRBLCCKE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  70.2
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  2-Allyloxymethyl-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadecane 在 PtCl₆*H₂O sodium carbonate 作用下， 以 四氢呋喃 、 甲苯 、 乙腈 为溶剂， 反应 15.0h， 生成
  参考文献：
  名称：

  Efficient Immobilization of a Cadmium Chemosensor in a Thin Film:  Generation of a Cadmium Sensor Prototype

  摘要：

  The development of an ion-selective chemosensor for Cd2+ allows generation of a "real-time" sensor, Immobilization of the chemosensor on quartz was achieved in a simple monolayer and in a thin film using a polymer intermediary. As intended, the thin film contains much more chemosensor than the monolayer and provides measurable responses to aqueous Cd2+ concentrations below 1 mu M. Alkali and alkaline earth ions do not interfere with Cd2+ sensing; Zn2+ and Cu2+ are potential interferents.

  DOI：

  10.1021/ol050027t
• 作为产物：
  描述：

  1,8-二氨基-3,6-二氧杂辛烷 、 4-<(allyloxy)methyl>-1,8-diiodo-3,6-dioxaoctane 在 碳酸氢钠 作用下， 以 乙腈 为溶剂， 反应 48.0h， 以52%的产率得到2-Allyloxymethyl-1,4,10,13-tetraoxa-7,16-diaza-cyclooctadecane
  参考文献：
  名称：

  Efficient Immobilization of a Cadmium Chemosensor in a Thin Film:  Generation of a Cadmium Sensor Prototype

  摘要：

  The development of an ion-selective chemosensor for Cd2+ allows generation of a "real-time" sensor, Immobilization of the chemosensor on quartz was achieved in a simple monolayer and in a thin film using a polymer intermediary. As intended, the thin film contains much more chemosensor than the monolayer and provides measurable responses to aqueous Cd2+ concentrations below 1 mu M. Alkali and alkaline earth ions do not interfere with Cd2+ sensing; Zn2+ and Cu2+ are potential interferents.

  DOI：

  10.1021/ol050027t

文献信息

• Efficient Immobilization of a Cadmium Chemosensor in a Thin Film:  Generation of a Cadmium Sensor Prototype
  作者：R. Todd Bronson、David J. Michaelis、Randy D. Lamb、Ghaleb A. Husseini、Paul B. Farnsworth、Matthew R. Linford、Reed M. Izatt、Jerald S. Bradshaw、Paul B. Savage

  DOI：10.1021/ol050027t

  日期：2005.3.1

  The development of an ion-selective chemosensor for Cd2+ allows generation of a "real-time" sensor, Immobilization of the chemosensor on quartz was achieved in a simple monolayer and in a thin film using a polymer intermediary. As intended, the thin film contains much more chemosensor than the monolayer and provides measurable responses to aqueous Cd2+ concentrations below 1 mu M. Alkali and alkaline earth ions do not interfere with Cd2+ sensing; Zn2+ and Cu2+ are potential interferents.