甘油二羟基硬脂酸酯 | 122546-20-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 中文名称: 甘油二羟基硬脂酸酯
• 英文名称: 2,3-Dihydroxypropyl 2,2-dihydroxyoctadecanoate
• CAS: 122546-20-7
• 化学式: C₂₁H₄₂O₆
• 分子量: 390.6
• InChiKey: NJWOORNSRKNXJS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  27
• 可旋转键数：
  20
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• UV ABSORBER FORMULATIONS
  申请人：Acker Stephanie

  公开号：US20100111884A1

  公开（公告）日：2010-05-06

  Disclosed is a UV filter composition comprising (a) an organic UV absorber of formula (1), wherein R 1 and R 2 , independently of one another, are C 3 -C 18 alkyl; C 2 -C 18 alkenyl; a radical of the formula —CH 2 —CH(OH)—CH 2 —O-T 1 ; or R 1 and R 2 are a radical of the formula (4a); R 7 is a direct bond; a straight-chain or branched C 1 -C 4 alkylene radical or a radical of the formula (I) or (II); R 8 , R 9 and R 10 , independently of one another, are C 1 -C 18 alkyl; C 1 -C 18 alkoxy or a radical of the formula (III); R 11 is C 1 -C 5 alkyl; m 1 is a number from 1 to 4; p 1 is 0; or a number from 1 to 5; A 1 is a radical of the formula (1b), (1c) or (1d); R 3 is hydrogen; C 1 -C 10 alkyl; —(CH 2 CHR 5 —O)n 1 -T 2 ; or —CH 2 —CH(—OH)—CH 2 —O-T 2 ; R 4 is hydrogen; M; C 1 -C 5 alkyl; or —(CH 2 )m 2 —O-T 3 ; R 5 is hydrogen; or methyl; T 1 , T 2 and T 3 independently from each other are hydrogen; or C 1 -C 18 alkyl; Q 1 is C 1 -C 18 alkyl, M is a metal cation; m 2 is 1 to 4; and n 1 is 1-16, (b) dimethyl capramide, (c) a cosmetically acceptable carrier; and water.

  本发明公开了一种紫外线过滤组合物，包括（a）式（1）的有机紫外线吸收剂，其中R1和R2独立地是C3-C18烷基；C2-C18烯基；式—CH2—CH（OH）—CH2—O-T1的基团；或者R1和R2是式（4a）的基团；R7是直链或支链C1-C4烷基、式（I）或（II）的基团；R8、R9和R10独立地是C1-C18烷基、C1-C18烷氧基或式（III）的基团；R11是C1-C5烷基；m1是1至4的数字；p1是0或1至5的数字；A1是式（1b）、（1c）或（1d）的基团；R3是氢、C1-C10烷基、式—（CH2CHR5—O）n1-T2或式—CH2—CH（—OH）—CH2—O-T2；R4是氢、M、C1-C5烷基或式—（CH2）m2—O-T3；R5是氢或甲基；T1、T2和T3互相独立地是氢或C1-C18烷基；Q1是C1-C18烷基，M是金属阳离子；m2是1至4的数字；n1是1-16，（b）二甲基辛酰胺，（c）化妆品可接受载体；和水。
• Linkage of agents using microparticles
  申请人：Green Howard

  公开号：US20060110379A1

  公开（公告）日：2006-05-25

  Methods, products and kits are provided for attaching agents to a skin surface via microparticles using endogenous or exogenous transglutaminase.

  提供了一种方法、产品和套件，可通过内源或外源性谷氨酰胺转移酶使用微粒子将药剂附着到皮肤表面。
• Formulation of UV absorbers by incorporation in solid lipid nanoparticles
  申请人：Ciba Speciality Chemicals Holding Inc.

  公开号：EP1378231A1

  公开（公告）日：2004-01-07

  Solid lipid nanoparticle compositions containing (a) 1 to 40% by weight of an oil-soluble UV absorber, (b) 20 to 98.9% by weight of a solid lipid, (c) 0.1 to 20% by weight of an emulsifier and (d) 0 to 40% by weight of a liquid lipid or a liquid oil-miscible UV absorber The compositions according to the invention enhance the solubility behaviour of oil-soluble UV filters in cosmetic formulations and thereby also improve their effectiveness.

  含有以下成分的固体脂质纳米颗粒组合物 (a) 1%至 40%（按重量计）的油溶性紫外线吸收剂、 (b) 20%至 98.9%（按重量计）的固体脂质、 (c) 0.1%至 20%（重量百分比）的乳化剂和 (d) 0 至 40%（重量百分比）的液态脂质或液态油溶性紫外线吸收剂 本发明的组合物可以提高油溶性紫外线过滤剂在化妆品配方中的溶解度，从而提高其功效。
• Substituted phenols as useful repellents for insects
  申请人：Ciba Specialty Chemicals Holding Inc.

  公开号：EP1417886A1

  公开（公告）日：2004-05-12

  The instant invention pertains to the use of substituted phenols as repellents for insects. The compounds may be applied in cosmetic formulations directly to the skin of humans or animals, they are, however also useful when applied to plastic materials such as polymer films or fibers, for example in clothings or tents. They may be even applied to clothes in a later stage, for example during washing or rinsing. A further aspect is a process for the manufacture of insect repellent substrates and surfaces.

  本发明涉及使用取代酚作为驱虫剂来驱除昆虫。这些化合物可以在化妆品配方中直接涂抹在人或动物的皮肤上，但也可以涂抹在塑料材料上，如聚合物薄膜或纤维上，例如在布料或帐篷中。它们甚至可以在稍后阶段，例如在洗涤或漂洗过程中涂在衣服上。另一个方面是制造驱虫剂基材和表面的工艺。
• Intercalated layered silicate
  申请人：Cryovac, Inc.

  公开号：EP2105411A1

  公开（公告）日：2009-09-30

  A method of exfoliating a layered silicate comprising: mixing from about 0.1 to about 100 weight parts of an intercalated layered silicate with 100 weight parts of a matrix medium to form a mixture, wherein: the intercalated layered silicate comprises: a layered silicate comprising a plurality of silicate layers; and an intercalating agent sorbed between the silicate layers in an amount effective to provide an average interlayer spacing between the silicate layers of at least about 20Å, wherein the intercalating agent is selected from one or more of fatty acid esters of sorbitan, fatty acid esters of glycerol, fatty acid amide waxes, variants of amide waxes, and variants of amides; and the matrix medium comprises one or more materials selected from: polymer selected from one or more of ethylene/vinyl alcohol copolymer, ionomer, vinyl plastic, polyamide, polyester, and polystyrene; energy curable polymer precursors; coating solvents, coating binders, and coating resins; ink solvents and ink resins; grease lubricating oils and grease gelling agents; cosmetic lipids, cosmetic emollients, cosmetic humectants, cosmetic film formers, cosmetic binders, cosmetic surfactants, and cosmetic solvents; pharmaceutical excipients; emulsions selected from an oil-in-water emulsion and a water-in-oil emulsion; and adding sufficient energy to the mixture to form a dispersed-particle composition comprising at least about 0.1 weight parts exfoliated particles per 100 weight parts matrix medium.

  一种剥离层状硅酸盐的方法，包括 将约 0.1 至约 100 重量份的夹层层状硅酸盐与 100 重量份的基质介质混合形成混合物，其中 夹层层状硅酸盐包括 由多个硅酸盐层组成的层状硅酸盐；以及 吸附在硅酸盐层之间的插层剂，其有效量可使硅酸盐层之间的平均层间距至少达到约 20 Å，其中插层剂选自山梨醇脂肪酸酯、甘油脂肪酸酯、脂肪酸酰胺蜡、酰胺蜡变体和酰胺变体中的一种或多种；以及 基质介质包括选自以下物质的一种或多种材料 选自乙烯/乙烯醇共聚物、离子聚合物、乙烯基塑料、聚酰胺、聚酯和聚苯乙烯中的一种或多种聚合物； 能量固化聚合物前体； 涂料溶剂、涂料粘合剂和涂料树脂； 油墨溶剂和油墨树脂； 油脂润滑油和油脂胶凝剂； 化妆品脂质、化妆品润肤剂、化妆品保湿剂、化妆品成膜剂、化妆品粘合剂、化妆品表面活性剂和化妆品溶剂； 药用辅料； 选自水包油乳液和油包水乳液的乳液；以及 向混合物中加入足够的能量，以形成分散颗粒组合物，该组合物包括每 100 重量份基质介质中至少约 0.1 重量份的脱落颗粒。