(S)-1-[2-(2-methoxyethoxy)ethoxy]propan-2-ol | 721922-68-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (S)-1-[2-(2-methoxyethoxy)ethoxy]propan-2-ol
• 英文别名: (S)-1-(2-(2-Methoxyethoxy)ethoxy)propan-2-ol；(2S)-1-[2-(2-methoxyethoxy)ethoxy]propan-2-ol
• CAS: 721922-68-5
• 化学式: C₈H₁₈O₄
• 分子量: 178.229
• InChiKey: MCBRLKGIOZXDOU-QMMMGPOBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  12
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (S)-1-[2-(2-methoxyethoxy)ethoxy]propan-2-ol 在 硼烷四氢呋喃络合物 、 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 反应 14.5h， 生成 3-{(S)-2-[2-(2-Methoxy-ethoxy)-ethoxy]-1-methyl-ethoxy}-2-{(S)-2-[2-(2-methoxy-ethoxy)-ethoxy]-1-methyl-ethoxymethyl}-propan-1-ol
  参考文献：
  名称：

  Anion-Directed Self-Assembly of Coordination Polymer into Tunable Secondary Structure

  摘要：

  A bent-shaped bipyridine ligand containing a dendritic aliphatic side chain has been synthesized as a ligand and complexed with silver ion through a self-assembling process. The resulting complexes were observed to self-assemble into supramolecular structures that differ significantly as a function of the counteranion size in the solid state, as confirmed by 1-D and 2-D X-ray diffraction experiments. The secondary structure of a cationic coordination chain appears to be dependent on the size of the counteranion. As the size of anion increases, the secondary structure of the coordination chain changes, from a helical chain, via a dimeric cycle, to a zigzag chain in the solid state. Interestingly, dilute solutions of the complexes exhibiting a columnar structure in polar solvents undergo spontaneous gelation and the resulting gels display a significant Cotton effect in the chromophore of the aromatic unit. These results represent a significant example that small variation in the anion size can provide a useful strategy to manipulate the secondary structure of linear chain and thereby solid-state supramolecular structure.

  DOI：

  10.1021/ja049799v
• 作为产物：
  描述：

  2-(2-甲氧基乙氧基)乙基4-甲基苯磺酸负离子 在 sodium hydride 、 对甲苯磺酸 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 4.0h， 生成 (S)-1-[2-(2-methoxyethoxy)ethoxy]propan-2-ol
  参考文献：
  名称：

  Anion-Directed Self-Assembly of Coordination Polymer into Tunable Secondary Structure

  摘要：

  A bent-shaped bipyridine ligand containing a dendritic aliphatic side chain has been synthesized as a ligand and complexed with silver ion through a self-assembling process. The resulting complexes were observed to self-assemble into supramolecular structures that differ significantly as a function of the counteranion size in the solid state, as confirmed by 1-D and 2-D X-ray diffraction experiments. The secondary structure of a cationic coordination chain appears to be dependent on the size of the counteranion. As the size of anion increases, the secondary structure of the coordination chain changes, from a helical chain, via a dimeric cycle, to a zigzag chain in the solid state. Interestingly, dilute solutions of the complexes exhibiting a columnar structure in polar solvents undergo spontaneous gelation and the resulting gels display a significant Cotton effect in the chromophore of the aromatic unit. These results represent a significant example that small variation in the anion size can provide a useful strategy to manipulate the secondary structure of linear chain and thereby solid-state supramolecular structure.

  DOI：

  10.1021/ja049799v

文献信息

• Self-Assembly of Photochromic Diarylethenes with Amphiphilic Side Chains: Core-Chain Ratio Dependence on Supramolecular Structures
  作者：Takashi Hirose、Masahiro Irie、Kenji Matsuda

  DOI：10.1002/asia.200800340

  日期：2009.1.5

  diarylethene derivatives having different lengths and numbers of poly(ethylene glycol) side chains were synthesized and their photochromic property and self‐assembling behavior were investigated. The self‐assembling behavior of the derivatives strongly depends upon the ratio between the hydrophobic core and the amphiphilic side chain. According to UV/Vis absorption spectroscopy, CD spectroscopy, and dynamic light

  合成了具有不同长度和数量的聚乙二醇侧链的光致变色二芳基乙烯衍生物，并研究了它们的光致变色性能和自组装行为。衍生物的自组装行为在很大程度上取决于疏水核与两亲侧链之间的比例。根据UV / Vis吸收光谱，CD光谱和动态光散射实验，这些衍生物显示出组装结构的不同尺寸分布和在水中的不同溶解度。在闭环异构体中观察到的诱导CD信号的强度对于具有两个六甘醇侧链的分子是最大的。研究了核心链比率与自组装结构规律性之间的关系。
• 两亲性分子化合物、制备方法、两亲性的纳米材料
  申请人：中国科学技术大学

  公开号：CN113999144A

  公开（公告）日：2022-02-01

  本发明公开了两亲性分子化合物、制备方法、两亲性的纳米材料，两亲性分子化合物包括：手性的双烷基、氨基甲酸酯连接的苯环链段和手性甘醇链段。
• Anion-Directed Self-Assembly of Coordination Polymer into Tunable Secondary Structure
  作者：Ho-Joong Kim、Wang-Cheol Zin、Myongsoo Lee

  DOI：10.1021/ja049799v

  日期：2004.6.1

  A bent-shaped bipyridine ligand containing a dendritic aliphatic side chain has been synthesized as a ligand and complexed with silver ion through a self-assembling process. The resulting complexes were observed to self-assemble into supramolecular structures that differ significantly as a function of the counteranion size in the solid state, as confirmed by 1-D and 2-D X-ray diffraction experiments. The secondary structure of a cationic coordination chain appears to be dependent on the size of the counteranion. As the size of anion increases, the secondary structure of the coordination chain changes, from a helical chain, via a dimeric cycle, to a zigzag chain in the solid state. Interestingly, dilute solutions of the complexes exhibiting a columnar structure in polar solvents undergo spontaneous gelation and the resulting gels display a significant Cotton effect in the chromophore of the aromatic unit. These results represent a significant example that small variation in the anion size can provide a useful strategy to manipulate the secondary structure of linear chain and thereby solid-state supramolecular structure.