11-(2-hydroxynaphthalen-1-yl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one | 326611-30-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯二氮卓类
• 英文名称: 11-(2-hydroxynaphthalen-1-yl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
• 英文别名: 6-(2-hydroxynaphthalen-1-yl)-9,9-dimethyl-6,8,10,11-tetrahydro-5H-benzo[b][1,4]benzodiazepin-7-one
• CAS: 326611-30-7
• 化学式: C₂₅H₂₄N₂O₂
• 分子量: 384.478
• InChiKey: CHOZSSSKKCJHKA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  29
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  61.4
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1-(((2-aminophenyl)imino)methyl)naphthalen-2-ol 、 5,5-二甲基-1,3-环己二酮 在 对甲苯磺酸 作用下， 以 正丁醇 为溶剂， 以67%的产率得到11-(2-hydroxynaphthalen-1-yl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
  参考文献：
  名称：

  11-R-dibenzo[b,e][1,4]diazepin-1-ones, the chemosensors for transition metal cations

  摘要：

  A series of 11-R-dibenzo[b,e][1,4]diazepin-1-ones was synthesized. The luminescence, complex formation, and redox properties of these compounds were investigated. The 11-(anthracen-9-yl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one was found to be an effective and selective fluorescent chemosensor for Cd2+ cations.

  DOI：

  10.1134/s1070363212070109

文献信息

• 11-R-dibenzo[b,e][1,4]diazepin-1-ones, the chemosensors for transition metal cations
  作者：I. E. Tolpygin、N. V. Mikhailenko、A. A. Bumber、E. N. Shepelenko、U. V. Revinsky、A. D. Dubonosov、V. A. Bren’、V. I. Minkin

  DOI：10.1134/s1070363212070109

  日期：2012.7

  A series of 11-R-dibenzo[b,e][1,4]diazepin-1-ones was synthesized. The luminescence, complex formation, and redox properties of these compounds were investigated. The 11-(anthracen-9-yl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one was found to be an effective and selective fluorescent chemosensor for Cd2+ cations.