| 225505-00-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 225505-00-0
• 化学式: C₄₀H₆₇NO₁₃
• 分子量: 769.971
• InChiKey: PPQKEQVKVQBWJO-IVUGULFHSA-N

反应信息

• 作为反应物：
  描述：

  在 potassium carbonate 作用下， 以 甲醇 、 水 为溶剂， 以96%的产率得到
  参考文献：
  名称：

  Preparation of 9-deoxo-4″-deoxy-6,9-epoxyerythromycin lactams “motilactides”: Potent and orally active prokinetic agents

  摘要：

  A series of new, highly potent and orally active "motilactides", 9-deoxo-4 "-deoxy-6,9-epoxyerythromycin lactams was designed, synthesized, and evaluated for their gastrointestinal motor stimulating activity. These compounds were acid stable and showed good oral efficacy. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(98)00111-5
• 作为产物：
  描述：

  [(2S,3R,4S,6R)-4-(dimethylamino)-2-[[(1R,2R,5R,6S,7S,8R,9R,11R,12S,13S,14R)-2-ethyl-9,12-dihydroxy-6-[(2S,4S,6S)-4-methoxy-4,6-dimethyloxan-2-yl]oxy-1,5,7,9,11,13-hexamethyl-4,16-dioxo-3,15,17-trioxabicyclo[12.3.0]heptadecan-8-yl]oxy]-6-methyloxan-3-yl] acetate 在 吡啶 、 trifluoromethanesulfonic acid anhydride 作用下， 以 二氯甲烷 为溶剂， 以89%的产率得到
  参考文献：
  名称：

  Preparation of 9-deoxo-4″-deoxy-6,9-epoxyerythromycin lactams “motilactides”: Potent and orally active prokinetic agents

  摘要：

  A series of new, highly potent and orally active "motilactides", 9-deoxo-4 "-deoxy-6,9-epoxyerythromycin lactams was designed, synthesized, and evaluated for their gastrointestinal motor stimulating activity. These compounds were acid stable and showed good oral efficacy. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(98)00111-5