| 872598-68-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 872598-68-0
• 化学式: C₂₂H₂₇NO₆
• 分子量: 401.459
• InChiKey: YCBCQVIWLQBWFE-OOZXPGRNSA-N

反应信息

• 作为反应物：
  描述：

  在 sodium tetrahydroborate 作用下， 以 甲醇 为溶剂， 反应 1.5h， 生成 (2'S)-hydroxystemofoline 、 (2'R)-hydroxystemofoline
  参考文献：
  名称：

  Phytochemical Studies on Stemona Plants:  Isolation of Stemofoline Alkaloids

  摘要：

  Six new stemofoline alkaloids, (2'R)-hydroxystemofoline (5), (3'R)-stemofolenol (6), (3'S)-stemofolenol (7), 1',2'-didehydrostemofoline-N-oxide (8), the first C-19 stemofoline alkaloid, methylstemofoline (9), and the first glycosidated Stemona alkaloid, stemofolinoside (10), and three known alkaloids, (2'S)-hydroxystemofoline (2), (11Z)-l',2'-didehydrostemofoline (3), and (11E)-l',2'-didehydrostemofoline (4), have been isolated from a root extract of an unidentified Stemona species. The structure and relative configuration of these new alkaloids have been determined by spectral data interpretation and from semisynthetic studies.

  DOI：

  10.1021/np050361y
• 作为产物：
  描述：

  (2'S)-hydroxystemofoline 在 碳酸氢钠 、 戴斯-马丁氧化剂 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以97%的产率得到
  参考文献：
  名称：

  Phytochemical Studies on Stemona Plants:  Isolation of Stemofoline Alkaloids

  摘要：

  Six new stemofoline alkaloids, (2'R)-hydroxystemofoline (5), (3'R)-stemofolenol (6), (3'S)-stemofolenol (7), 1',2'-didehydrostemofoline-N-oxide (8), the first C-19 stemofoline alkaloid, methylstemofoline (9), and the first glycosidated Stemona alkaloid, stemofolinoside (10), and three known alkaloids, (2'S)-hydroxystemofoline (2), (11Z)-l',2'-didehydrostemofoline (3), and (11E)-l',2'-didehydrostemofoline (4), have been isolated from a root extract of an unidentified Stemona species. The structure and relative configuration of these new alkaloids have been determined by spectral data interpretation and from semisynthetic studies.

  DOI：

  10.1021/np050361y