(2S)-2-N-ethyl-1-N,2-N-bis(4-methyl-1,3-thiazol-2-yl)propane-1,2-diamine | 1220182-58-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: (2S)-2-N-ethyl-1-N,2-N-bis(4-methyl-1,3-thiazol-2-yl)propane-1,2-diamine
• CAS: 1220182-58-0
• 化学式: C₁₃H₂₀N₄S₂
• 分子量: 296.461
• InChiKey: SXRKPCKHTOKEKZ-NSHDSACASA-N

反应信息

• 作为产物：
  描述：

  (2S)-3-methyl-1-N,2-N-bis(4-methyl-1,3-thiazol-2-yl)butane-1,2-diamine 在 氢氟酸 作用下， 反应 1.5h， 生成 (2S)-2-N-ethyl-1-N,2-N-bis(4-methyl-1,3-thiazol-2-yl)propane-1,2-diamine
  参考文献：
  名称：

  Synthesis of Chiral Polyaminothiazoles

  摘要：

  An efficient approach toward the parallel solid-phase synthesis of highly diversified chiral polyaminothiazoles employing Hantzsc’s thiazole synthesis is presented. The treatment of resin-bound chiral polyamines with Fmoc-isothiocyanates generated polythioureas which were further reacted with a variety of α-halogenoketones to afford following cleavage from the solid support the desired chiral polyaminothiazoles in good yield and purity.

  DOI：

  10.1021/cc9001907