(E)-3-(benzotriazol-1-yl)-3-(2,3-dimethylphenyl)-1-phenyl-2-(4-tolyl)prop-2-en-1-one | 1215004-49-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: (E)-3-(benzotriazol-1-yl)-3-(2,3-dimethylphenyl)-1-phenyl-2-(4-tolyl)prop-2-en-1-one
• CAS: 1215004-49-1
• 化学式: C₃₀H₂₅N₃O
• 分子量: 443.548
• InChiKey: PGTPNWWKYSNTCT-ZQHSETAFSA-N

反应信息

• 作为产物：
  描述：

  3-(benzotriazol-1-yl)-3-(2,3-dimethylphenyl)-1-phenyl-2-(4-tolyl)prop-2-en-1-ol 在 potassium dichromate 、 硫酸 作用下， 以 四氢呋喃 为溶剂， 反应 0.5h， 生成 (Z)-3-(benzotriazol-1-yl)-3-(2,3-dimethylphenyl)-1-phenyl-2-(4-tolyl)prop-2-en-1-one 、 (E)-3-(benzotriazol-1-yl)-3-(2,3-dimethylphenyl)-1-phenyl-2-(4-tolyl)prop-2-en-1-one
  参考文献：
  名称：

  Practical method for synthesis of 2,3-disubstituted indole derivatives promoted by β-(benzotriazol-1-yl)allylic O-stannyl ketyl radicals

  摘要：

  Treatment of beta-aryl-beta-(benzotriazol-1-yl)-alpha-primary alkyl (or aryl)-alpha,beta-unsaturated ketones 1 with n-Bu3SnH (4 equiv) in a catalytic amount of AlBN in PhH at reflux afforded 3-alkyl (or aryl)-2-arylindoles 8 in good yields. However, when tert-butyl group is bonded at alpha-position, 3-acyl (or aroyl)-2-arylindoles 9 were obtained as major products along with phenanthridines 5 as minor products. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.12.030