(E)-(S)-5-Amino-5-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-pent-2-enoic acid ethyl ester | 809281-18-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧吡喃
• 英文名称: (E)-(S)-5-Amino-5-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-pent-2-enoic acid ethyl ester
• CAS: 809281-18-3
• 化学式: C₁₈H₂₉NO₇
• 分子量: 371.431
• InChiKey: GWUDVWFSAPSWQX-INSUUBLWSA-N

反应信息

• 作为反应物：
  描述：

  二碳酸二叔丁酯 、 (E)-(S)-5-Amino-5-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-pent-2-enoic acid ethyl ester 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 3.0h， 生成 (E)-(S)-5-tert-Butoxycarbonylamino-5-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-pent-2-enoic acid ethyl ester
  参考文献：
  名称：

  The stereoselective synthesis of C-linked 4′-deoxy aza-disaccharides from C-linked carbo-β-amino acids

  摘要：

  The stereoselective synthesis of 4'-deoxy aza-disaccharides in a concise and practical approach is described from C-linked carbo-beta-amino acid esters and this protocol utilizes an intramolecular amide bond formation and cis-dihydroxylation for the construction of the new sugar ring. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.10.014
• 作为产物：
  描述：

  methyl 3-[2,2,7,7-tetramethylperhydrobis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl]-3-(benzylamino)propanoate 在 palladium on activated charcoal lithium aluminium tetrahydride 、 氢气 、 三乙胺 、 三氟乙酸 、 2-碘酰基苯甲酸 作用下， 以 四氢呋喃 、 甲醇 、 二氯甲烷 、 二甲基亚砜 为溶剂， 反应 46.0h， 生成 (E)-(S)-5-Amino-5-((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-yl)-pent-2-enoic acid ethyl ester
  参考文献：
  名称：

  The stereoselective synthesis of C-linked 4′-deoxy aza-disaccharides from C-linked carbo-β-amino acids

  摘要：

  The stereoselective synthesis of 4'-deoxy aza-disaccharides in a concise and practical approach is described from C-linked carbo-beta-amino acid esters and this protocol utilizes an intramolecular amide bond formation and cis-dihydroxylation for the construction of the new sugar ring. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.10.014