甲基3,4-O-(氧代亚甲基)-beta-D-吡喃半乳糖苷 | 136113-05-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧吡喃
• 中文名称: 甲基3,4-O-(氧代亚甲基)-beta-D-吡喃半乳糖苷
• 英文名称: Methyl-3,4-O-carbonyl-beta-D-galactopyranoside
• 英文别名: (3aS,4R,6R,7R,7aR)-7-hydroxy-4-(hydroxymethyl)-6-methoxy-4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2-one
• CAS: 136113-05-8
• 化学式: C₈H₁₂O₇
• 分子量: 220.179
• InChiKey: NJYOQQXXQNRVOI-XUUWZHRGSA-N

物化性质

• 沸点：
  507.5±50.0 °C(Predicted)
• 密度：
  1.52±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  94.4
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  2-Thioxo-thiazolidine-3-carboxylic acid isobutyl ester 、 甲基-Β-D-吡喃半乳糖苷 在 sodium hydride 作用下， 以 吡啶 为溶剂， 反应 24.0h， 以90%的产率得到甲基3,4-O-(氧代亚甲基)-beta-D-吡喃半乳糖苷
  参考文献：
  名称：

  从不受保护的甲基d-糖苷制备环状和无环碳酸酯的新颖便捷途径

  摘要：

  通过使用噻唑烷-2-硫酮和2-巯基-5-甲基-1,3,4-噻二唑烷氧基羰基或羰基衍生物将未保护的甲基D-糖苷选择性地酰化。在合适的条件下，可获得相应的6-O-烷氧基羰基化合物或环状的五元或六元碳酸酯。

  DOI：

  10.1016/0040-4039(91)85076-h

文献信息

• Isocyanate-free synthesis of carbonate-modified polymers
  申请人：Evonik Degussa GmbH

  公开号：US10202488B2

  公开（公告）日：2019-02-12

  The present invention relates to an isocyanate-free and preferably solvent-free process for preparing polymers containing five-membered cyclic carbonate groups. In particular, the present invention is directed to a process for preparing polymers bearing cyclic carbonate groups by reacting carboxyl-bearing polymers selected from the group including polyesters based on di- or polyols and di- or polycarboxylic acids or derivatives thereof or poly(meth)acrylates, with hydroxyl-functionalized five-membered cyclic carbonates, without addition of isocyanates.

  本发明涉及一种用于制备含有五元环碳酸酯基团的聚合物的无异氰酸酯且优选无溶剂工艺。特别是，本发明涉及一种制备含环状碳酸酯基团的聚合物的工艺，该工艺是在不添加异氰酸酯的情况下，使选自基于二元或多元醇和二元或多元羧酸或其衍生物或聚（甲基）丙烯酸酯的聚酯组的含羧基聚合物与羟基官能化的五元环状碳酸酯反应。
• ISOCYANATE-FREE SYNTHESIS OF CARBONATE-MODIFIED POLYMERS
  申请人：Evonik Degussa GmbH

  公开号：US20170355814A1

  公开（公告）日：2017-12-14

  The present invention relates to an isocyanate-free and preferably solvent-free process for preparing polymers containing five-membered cyclic carbonate groups. In particular, the present invention is directed to a process for preparing polymers bearing cyclic carbonate groups by reacting carboxyl-bearing polymers selected from the group including polyesters based on di- or polyols and di- or polycarboxylic acids or derivatives thereof or poly(meth)acrylates, with hydroxyl-functionalized five-membered cyclic carbonates, without addition of isocyanates.
• ISOCYANATE-FREE REACTIVE POLYURETHANE COMPOSITIONS
  申请人：Evonik Degussa GmbH

  公开号：US20180291153A1

  公开（公告）日：2018-10-11

  The present invention relates to isocyanate-free polyurethane composition for adhesives, sealants and coating materials. In particular, the present invention relates to isocyanate-free polyurethane composition including polymers (A) carrying cyclic carbonate groups, which do not comprise or are not based on isocyanates, obtained by reaction of polymers which carry carboxyl groups, selected from the group encompassing polyesters based on diols or polyols and on dicarboxylic or polycarboxylic acids and/or derivatives thereof, or poly(meth)acrylates, with five-membered cyclic carbonates that are functionalized with hydroxyl groups, and a curing agent (B) having at least one amino group and at least one further functional group, wherein the further functional group is not an isocyanate group.
• A novel and convenient route to cyclic and acyclic carbonates from unprotected methyl d-glycosides
  作者：Monique Allainmat、Daniel Plusquellec

  DOI：10.1016/0040-4039(91)85076-h

  日期：1991.6

  Unprotected methyl D-glycosides were selectively acylated by using thiazolidine-2-thione and 2-mercapto-5-methyl-1,3,4-thiadiazole alkoxycarbonyl or carbonyl derivatives. Under suitable conditions the corresponding 6-O-alkoxycarbonyl compounds or the cyclic Five or six membered carbonates could be obtained.

  通过使用噻唑烷-2-硫酮和2-巯基-5-甲基-1,3,4-噻二唑烷氧基羰基或羰基衍生物将未保护的甲基D-糖苷选择性地酰化。在合适的条件下，可获得相应的6-O-烷氧基羰基化合物或环状的五元或六元碳酸酯。