(E)-6,7-dimethylocta-3,6-dien-2-ol | 1345735-03-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (E)-6,7-dimethylocta-3,6-dien-2-ol
• CAS: 1345735-03-6
• 化学式: C₁₀H₁₈O
• 分子量: 154.252
• InChiKey: GFSJLBPGBZKRKI-FNORWQNLSA-N

反应信息

• 作为产物：
  描述：

  3-丁烯-2-醇 、 2,3-二甲基-1,3-丁二烯 在 C₃₅H₃₈O₅P₂*Br₂Co 、 zinc(II) iodide 、 锌 作用下， 以 二氯甲烷 为溶剂， 生成 (E)-6,7-dimethylocta-3,6-dien-2-ol 、 5,6-dimethyl-3-methylenehept-5-en-2-ol
  参考文献：
  名称：

  Gaining Absolute Control of the Regiochemistry in the Cobalt-Catalyzed 1,4-Hydrovinylation Reaction

  摘要：

  The absolute control of the regiochemistry of a cobalt-catalyzed 1,4-hydrovinylation reaction is achieved by alternation of the ligands applied. While the dppe/dppp ligands led to the formation of the branched product, the herein described application of the SchmalzPhos ligand generates the corresponding linear product in both excellent yields and regioselectivities. The catalyst system exhibits a high tolerance toward functional groups, and the very mild reaction conditions allow the synthesis of 1,4-dienes without isomerization into conjugated systems.

  DOI：

  10.1021/ol202696n