| 1016274-24-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1016274-24-0
• 化学式: C₂₆H₃₁F₃O₆
• 分子量: 496.524
• InChiKey: MESAJBPJCJTRKZ-JNCDRMAQSA-N

反应信息

• 作为产物：
  描述：

  pestalotheol C 、 (R)-methoxytrifluoromethylphenylacetyl chloride 以 氘代吡啶 为溶剂， 反应 24.0h， 生成
  参考文献：
  名称：

  Pestalotheols A−D, Bioactive Metabolites from the Plant Endophytic Fungus Pestalotiopsis theae

  摘要：

  Pestalotheols A-D (1-4), four new metabolites, have been isolated from cultures of an isolate of the plant endophytic fungus Pestalotiopsis theae. The structures of these compounds were determined by NMR spectroscopy, and 1 is further confirmed by X-ray crystallography. The absolute configurations of compounds 1 and 3 were assigned by application of the modified Mosher method. Pestalotheol C (3) displayed an inhibitory effect on HIV-1(LAI) replication in C8166 cells with an EC50 value of 16.1 mu M.

  DOI：

  10.1021/np700744t